Jeff Spraggins

WORK HISTORY

EDUCATION

SKILLS

ABOUT JEFF SPRAGGINS

I am a faculty member in the Departments of Cell & Developmental Biology, Biochemistry, and Chemistry, Director of the Biomolecular Multimodal Imaging Center (BIOMIC), and a Director of the Mass Spectrometry Research Center at Vanderbilt University in Nashville, TN. My research focuses on the development of next-generation molecular imaging technologies and advanced applications for imaging mass spectrometry (IMS). One point of focus has been on developing high performance instrumentation to maximize spatial resolution, sensitivity, and molecular specificity for molecular imaging experiments. I have also been part of a team focused on multimodal image fusion. This work aims to create new imaging modalities that synergistically combine data from different imaging experiments (e.g. microscopy and IMS). Recently, my research group has begun to apply these advanced imaging technologies for the construction and analysis of 3-D multimodal molecular atlases. As part of the Human Biomolecular Atlas Program (HuBMAP, NIH), I am working on bringing together 3-D imaging mass spectrometry with a variety of in vivo and ex vivo imaging technologies to create new modalities of molecularly-informed biomedical imaging.