John Wagner
Leading Biopharmaceutical Executive • Entrepreneur • Physician • Scientist • Translational Medicinist
- Role
- Chief Medical Officer at Tempero Bio
- Location
- Cambridge, MA, US
- LinkedIn followers
- 500 followers
About John Wagner
Over 20 years of experience in biopharmaceuticals, drug discovery and development, translational medicine, experimental medicine, clinical pharmacology, biomarkers and surrogate endpoints, modeling and simulation, precompetitive collaboration, project leadership and management, portfolio management and prioritization, and scientific strategy. Responsible for over 150 introductions-to-humans, and instrumental to regulatory filings of Cancidas (caspofungin), Emend (aprepitant) Fosamax Plus (alendronate-vitamin D combination), Invanz (ertapenem) Isentress (raltegravir), Janumet (metformin-sitagliptin combination), Januvia (sitagliptin), Maxalt (rizatriptan), Ninlaro (ixazomib), Victrelis (boceprevir) and Zolinza (vorinostat). Drug development experience includes bone, cardiovascular, diabetes and metabolism, gastroenterology, infectious diseases, neuroscience, oncology, rare diseases, respiratory, rheumatology and immunology. Regulatory interactions include experience from the US (e.g, pre-IND, IND, End-of-Phase-2), Europe (particularly exploratory CTA submissions in Belgium), and Asia (China and Japan).Recognized for deep industry experience, scientific rigor, exploratory development mindset, innovation, results-orientation, ability to deliver valuable pipeline products, bold vision, optimistic leadership style and change management, collaboration and influencing, business acumen and wide experience across multiple therapeutic areas. A sought after mentor, noted for strong leadership and interpersonal skills, proficiency in building teams across varied settings, and ability to identify, hire and develop key talent.M.D. from Stanford University School of Medicine and Ph.D. from the Johns Hopkins University School of Medicine. Postgraduate training included Internal Medicine Internship and Residency and Molecular and Clinical Pharmacology Postdoctoral Fellowships at Stanford.Over 250 peer-reviewed scientific publications.
Experience
Chief Medical Officer
Apr 2025 — Present
Education
The Johns Hopkins University
M.A.
The Johns Hopkins University School of Medicine
PhD, Neuroscience and Pharmacology
The Johns Hopkins University
B.A.
Stanford University School of Medicine
MD, Medicine
Skills
- Pharmacovigilance
- Molecular Biology
- Clinical Development
- Neuroscience
- Medicine
- Medical Affairs
- Translational Medicine
- Regulatory Affairs
- Lifesciences
- CRO
- Regulatory Submissions
- In Vivo
- Oncology
- Protocol
- Pharmacokinetics
- Clinical Trials
- Cell Biology
- Neurology
- Pharmaceutical Industry
- Fda
- Experimental Medicine
- Biotechnology
- Drug Discovery
- Cell
- Clinical Study Design
- Immunology
- Diabetes
- Toxicology
- Medical Research
- Vaccines
- Clinical Research
- Clinical Pharmacology
- Validation
- Epidemiology
- Internal Medicine
- Biochemistry
- Life Sciences
- Therapeutic Areas
- Drug Development
- Pharmacology
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