John Wagner

Leading Biopharmaceutical Executive • Entrepreneur • Physician • Scientist • Translational Medicinist

Role
Chief Medical Officer at Tempero Bio
Location
Cambridge, MA, US
LinkedIn followers
500 followers
Healthcare & Human ServicesView LinkedIn profile

About John Wagner

Over 20 years of experience in biopharmaceuticals, drug discovery and development, translational medicine, experimental medicine, clinical pharmacology, biomarkers and surrogate endpoints, modeling and simulation, precompetitive collaboration, project leadership and management, portfolio management and prioritization, and scientific strategy. Responsible for over 150 introductions-to-humans, and instrumental to regulatory filings of Cancidas (caspofungin), Emend (aprepitant) Fosamax Plus (alendronate-vitamin D combination), Invanz (ertapenem) Isentress (raltegravir), Janumet (metformin-sitagliptin combination), Januvia (sitagliptin), Maxalt (rizatriptan), Ninlaro (ixazomib), Victrelis (boceprevir) and Zolinza (vorinostat). Drug development experience includes bone, cardiovascular, diabetes and metabolism, gastroenterology, infectious diseases, neuroscience, oncology, rare diseases, respiratory, rheumatology and immunology. Regulatory interactions include experience from the US (e.g, pre-IND, IND, End-of-Phase-2), Europe (particularly exploratory CTA submissions in Belgium), and Asia (China and Japan).Recognized for deep industry experience, scientific rigor, exploratory development mindset, innovation, results-orientation, ability to deliver valuable pipeline products, bold vision, optimistic leadership style and change management, collaboration and influencing, business acumen and wide experience across multiple therapeutic areas. A sought after mentor, noted for strong leadership and interpersonal skills, proficiency in building teams across varied settings, and ability to identify, hire and develop key talent.M.D. from Stanford University School of Medicine and Ph.D. from the Johns Hopkins University School of Medicine. Postgraduate training included Internal Medicine Internship and Residency and Molecular and Clinical Pharmacology Postdoctoral Fellowships at Stanford.Over 250 peer-reviewed scientific publications.

Experience

  1. Chief Medical Officer

    Tempero Bio

    Apr 2025 — Present

Education

  • The Johns Hopkins University

    M.A.

  • The Johns Hopkins University School of Medicine

    PhD, Neuroscience and Pharmacology

  • The Johns Hopkins University

    B.A.

  • Stanford University School of Medicine

    MD, Medicine

Skills

  • Pharmacovigilance
  • Molecular Biology
  • Clinical Development
  • Neuroscience
  • Medicine
  • Medical Affairs
  • Translational Medicine
  • Regulatory Affairs
  • Lifesciences
  • CRO
  • Regulatory Submissions
  • In Vivo
  • Oncology
  • Protocol
  • Pharmacokinetics
  • Clinical Trials
  • Cell Biology
  • Neurology
  • Pharmaceutical Industry
  • Fda
  • Experimental Medicine
  • Biotechnology
  • Drug Discovery
  • Cell
  • Clinical Study Design
  • Immunology
  • Diabetes
  • Toxicology
  • Medical Research
  • Vaccines
  • Clinical Research
  • Clinical Pharmacology
  • Validation
  • Epidemiology
  • Internal Medicine
  • Biochemistry
  • Life Sciences
  • Therapeutic Areas
  • Drug Development
  • Pharmacology

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John Wagner — Chief Medical Officer at Tempero Bio in Cambridge, MA, US | Unifers