John F. Thompson
NGS/genomics technology, gene therapy/editing, drug discovery/development, diagnostics
- Role
- Principal Application Scientist at Nabsys
- Location
- Providence, RI, US
- LinkedIn followers
- 500 followers
About John F. Thompson
Technology expert and problem-solving leader with strategic, technical and supervisory experience in diagnostics (cancer and rare disease), clinical genetics, next-generation sequencing instrument development, gene therapy, and pharmaceutical research and development• Precision medicine for cancer, rare disease, cardiovascular and metabolic disease therapies• Created superior clinical NGS assays for diagnosing rare pediatric diseases in CLIA, ISO15189, New York-state approved lab• Developed novel applications at two single-molecule, genomic analysis companies using SBS and nanopore/nanochannel technologies• Identified novel therapeutic targets and the genetic basis of drug response and drug-induced adverse events• Developed wide range of high throughput assays for drug discovery using small molecule binding, reporter genes, protein-protein interactions, and FRET• Spearheaded GWAS for cardiovascular and metabolic diseases and response to statins• Applied translational genomics technologies such as RNA-Seq, genetic variant detection with NGS and qPCR, ChIP-Seq, microarrays• Worked with experts in oncology, plant genetics, metagenomics/microbiomes, ancient DNA to develop NGS applications suited to needs
Experience
Principal Application Scientist
Jun 2023 — Present · Providence, RI, US
Education
University of California, Berkeley
PhD, Biophysical Chemistry
1978 — 1982
Yale University
BS, Chemistry
1975 — 1978
Skills
- Genomics
- Dna Analysis
- Sequencing
- Molecular Biology
- Genetics
- Drug Discovery
- Diagnostics
- Cell Based Assays
- Biotechnology
- Personalized Medicine
- Genetic Testing
- High Throughput Screening
- Dna Sequencing
- Dna
- In Vitro
- Lifesciences
- Biochemistry
- Cell
- Microarray
- Drug Development
- Proteomics
- Assay Development
- Oncology
- Product Development
- Translational Medicine
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