Joey Owusu-Sarfo
Phd Candidate @University Of Rhode Island College Of Pharmacy
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WORK HISTORY
Phd Candidate @University Of Rhode Island College Of Pharmacy
Kingston, RI, US
Investigate mitochondrial function and cardioprotective mechanisms, translating cellular findings into preclinical models, including ex vivo Langendorff heart perfusion.• Perform and optimize ROS, mitochondrial respiration, and supercomplex assays to assess bioenergetic function.• Design and propagate adenoviral vectors and perform mammalian cell transfections (H9c2, HEK293) to manipulate protein expression.• Validate constructs and protein localization using restriction analysis, sequencing, Western blotting, and confocal fluorescence imaging.• Manage molecular biology and cell culture workflows, including recombinant DNA manipulation and stable cell line development.• Conduct drug mechanism of action studies and integrate cellular and preclinical data to evaluate therapeutic potential.
EDUCATION
University of Rhode Island
Doctor of Philosophy, Pharmaceutical Sciences (Pharmacology & Toxicology)
Kwame Nkrumah University of Science and Technology, Kumasi
Pharmacy
ABOUT JOEY OWUSU-SARFO
I am a Pharmacologist and PhD Candidate at the University of Rhode Island, specializing in cardiovascular pharmacology, mitochondrial bioenergetics, and translational research. My work focuses on identifying molecular pathways that can be targeted for cardioprotection and therapeutic intervention.I have extensive expertise in mitochondrial respiration assays, ROS detection, supercomplex analysis, plasmid and viral vector design, adenoviral propagation, and mammalian cell culture, integrating molecular biology, preclinical cardiac models, and high-resolution imaging to uncover mechanisms of mitochondrial stress responses. I also have hands-on experience with ex vivo cardiac functional assays, including Langendorff heart perfusion, providing direct insight into cardiac physiology and drug responses.With a strong foundation as a PharmD, I bridge basic science discoveries with translational and therapeutic applications, contributing to both academic research and drug discovery initiatives. I am passionate about applying my expertise to advance cardiovascular therapeutics, bioenergetics-driven research, and preclinical development, while building collaborations across academic and industry settings.
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