J. Isaac Godfroy

About J. Isaac Godfroy

Scientist/Engineer with >10 years of experience in studying biological systems. I have worked with engineers, biochemists, organic chemists, and molecular biologists to answer critical questions in the fields of protein-protein interactions regulating the immune system, recombinant protein expression, and cell/gene therapy.Experienced in bioreactor process development and technology transfer for clinical manufacturing.I am a strong independent scientist, that is able to rapidly teach myself and implement new scientific methods to generate impactful results. I find working as a member of a strong team where there is an open exchange of ideas and teaching for personal growth to yield the best results. I enjoy working with others as I have a very outgoing and approachable demeanor that enjoys discussing scientific pursuits with team members.I’m interested in hearing from former colleagues and making new connections and can be reached through this profile.

Experience

1. Associate Director, Manufacturing Science and Technology

   Obsidian Therapeutics

   Dec 2025 — Present · Boston, MA, US

Education

• University of Colorado Boulder

  Ph.D., Chemical and Biological Engineering

  2009 — 2015

• University of Notre Dame

  B.S., Chemical and Biomolecular Engineering

  2005 — 2009

• University of Colorado Boulder

  Doctor of Philosophy - PhD, Chemical and Biomolecular Engineering

Skills

• Microscopy
• Cell Biology
• Protein Characterization
• Protein Purification
• Confocal Microscopy
• Facs
• Research
• Molecular Biology
• Fluorescence Microscopy
• Cell Culture
• Hplc
• Elisa
• Fret
• Gibson Assembly
• Biochemistry
• Vector Cloning
• Transfection
• Peptides
• Cell Based Assays
• Analytical Ultracentrifugation
• Lentivirus
• Uv/Vis
• Flow Cytometry
• Data Analysis
• Purification
• Protein Expression
• Fplc
• Vector Design
• Crispr/Cas9
• Directed Evolution
• Gel Electrophoresis
• Pcr
• Characterization
• Spectroscopy
• Western Blotting