Jim Wong

About Jim Wong

Vice President, Biological Sciences, OnKure TherapeuticsOver 17 years of experience leading innovative research and development initiatives as an in vitro molecular/cellular biologist, an in vivo pharmacologist, a group leader, and senior leadership in the biotech and pharma industries. Demonstrated expertise in target validation for oncology and immuno-oncology, small and large molecule drug discovery, regulatory documentation and compliance, and clinical-stage translational biology. Proven track record in driving pre-clinical data packages into clinical development by effective collaboration with cross-functional teams, including medicinal chemistry, computational chemistry, enzymology, cell biology, structural biology, in vitro ADME, in vivo DMPK, CMC, and clinical and commercial development. Known for integrating current literature, novel model development, cutting-edge omics tools, and collaborative external resources to accelerate pipeline progression.Areas of expertise- Oncology and immuno-oncology research- Molecular and cellular biology- In vivo pharmacology- Bioinformatics, transcriptomics, proteomics- Small and large molecule drug discovery- Research management and strategy- Regulatory documentation and compliance- New targets evaluationFormer positions:Senior Director, Director, and Senior Principal Scientist at Pfizer Boulder RU in Boulder, CO (Pharmacology)Research Investigator and Senior Research Scientist at Array Biopharma in Boulder, CO (Pharmacology)Senior Scientific Researcher at Genentech in SSF, CA (Cancer Immunology, Personalized Cancer Vaccines)Senior Scientist II, Senior Scientist, and Scientist at Oncomed Pharmaceuticals in Redwood City, CA (Target Validation)Postdoctoral Fellow at Genentech in SSF, CA (Marc Tessier-Lavigne Lab)Graduate Student at Stanford University in Stanford, CA (Guowei Fang Lab)

Experience

1. Vice President, Biological Sciences

   Onkure Therapeutics

   Aug 2024 — Present · Boulder, CO, US

Education

• Caltech

  B.S., Biology

  1996 — 2000

• Stanford University

  Ph.D., Biological Sciences

  2000 — 2006

Skills

• Pcr
• Flow Cytometry
• Protein Expression
• Western Blotting
• Immunofluorescence
• Dissection
• Biotechnology
• Protein Purification
• Biochemistry
• Microscopy
• Rt-Pcr
• Molecular Cloning
• Transfection
• Reverse Transcription Polymerase Chain Reaction (Rt-Pcr)
• Drug Discovery
• Cell Biology
• Qpcr
• Confocal Microscopy
• Assay Development
• Polymerase Chain Reaction (Pcr)
• Molecular Biology
• High Throughput Screening
• Mouse Models
• Real-Time Polymerase Chain Reaction (Qpcr)
• Cell Culture
• Western
• Life Sciences