Jie He

About Jie He

I’m a translational science leader motivated by enabling new precision medicine via innovative diagnostic solutions. I’m proud to have developed several market leader tissue and liquid based NGS diagnostic assays and biomarker products. With over 15 years of experiences in diagnostic biotech space, I’ve worked through all phases of diagnostic product development, particularly drawn into enabling the innovative biomarker solutions for biopharma partners and unveiling disease biology insights with exploratory biomarker analysis.My strength is being able to connect a strategic vision with end-to-end delivery. I’m experienced and efficient with cross function collaboration with internal team and external biopharma partners and academic collaborators KOLs.CORE COMPETENCIES• Clinical assay and biomarker strategy and implementation: Led end-to-end clinical assay and biomarker feasibility, development to validation and launch.• Translational biomarker strategy and execution: Designed and implemented biomarker plans to support internal and external clinical development, enabling data-driven insights into target engagement and patient stratification.• Strategic decision making and risk assessment: Applied translational research to inform go/no-go decisions, de-risking programs early by integrating preclinical and clinical data to guide portfolio strategy.• Bridging discovery and development: Aligned scientific hypotheses with clinical endpoints to ensure continuity across R&D phases, accelerating the translation of novel biomarkers into actionable clinical strategies.• Matrix Team Leadership: Led cross-functional teams spanning Assay Development, Computational Biology, Clinical Development, Regulatory, and Commercial functions to advance programs through development milestones.SKILLSOncology biomarker strategy | Translational science | Cross functional leadership | Biomarker analysis | Genomics | Partnership Development

Experience

1. Senior Director, Scientific Affairs

   Pillar Biosciences Incorporated

   Aug 2025 — Present · Natick, MA, US

Education

• The University of Toledo

  Ph.D, Bioinformatics, molecular biology

  2005 — 2009

Skills

• Statistics
• Genetics
• Mysql
• Sequence Analysis
• Phylogenetics
• Qpcr
• Rna
• Hardware Diagnostics
• Genomics
• Lifesciences
• Computational Biology
• Dna Sequencing
• Data Analysis
• Blast
• Cancer
• Molecular Biology
• Bioinformatics
• Python
• Analysis
• Perl
• Sequencing
• High Throughput Screening
• Biology
• Research
• Algorithms
• Biotechnology
• R
• Pcr
• Data Mining
• Biochemistry
• Dna