Jichun

Role
Director at Sparx Biopharmaceutical Corp
Location
Germantown, MD, US
LinkedIn followers
500 followers

Experience

  1. Director

    Sparx Biopharmaceutical Corp

    Sep 2019 — Present

    Lead antibody discovery teams for bispecific and multi-specific antibody design, and antibody engineering.• Lead scale-up and scale-down downstream process development• Lead downstream antibody production, including affinity chromatography, ion exchange chromatography, viral clearance, TFF, and formulation.• Lead protein expression and purification team for protein production using bacterial, yeast, baculovirus, and mammalian expression systems.• Lead phage display team to construct immune and synthetic phage libraries and screening• Lead analytical team for antibody biophysical characterizations, including SE-HPLC, CEX, DLS analyses, as well as SDS-PAGE, western blot, ELISA for purity analyses.• Lead efforts for cell line development and upstream process development, including 50-200 liter bioreactor process.

Skills

  • Antibodies
  • Purification
  • Protein Chemistry
  • Proein Analytical Techniques (Hplc, Ms, Sds-Page, Native Page, Dymamic Light Scarering, Etc.)
  • Pharmaceutical Industry
  • Molecular Cloning
  • Ion Channels
  • Structural Biology
  • Membrane Protein Purification
  • Molecular Biology
  • Protein Purification
  • Membrane Proteins
  • Drug Discovery
  • Gpcrs
  • Membrane Protein Expression
  • Cell Biology
  • Cell Culture
  • Biochemistry
  • Western Blotting
  • Protein Crystallization
  • Protein Expression

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Jichun — Director at Sparx Biopharmaceutical Corp in Germantown, MD, US | Unifers