Jian Han

About Jian Han

I am a scientist, inventor, and entrepreneur. As a scientist, I am interested in developing “the ultimate diagnostic”. Using multiplex PCR to amplify immune repertoire (T and B cell receptors) for NextGen sequencing, we identify disease-specific biomarkers, evaluate vaccines, and develop new therapeutics. As an inventor, I developed the award-winning tem-PCR technology that makes molecular differential diagnosis possible. The tem-PCR technology is a highly specific and sensitive multiplex PCR technology that also can be automated. We have now developed two multiplex methods called arm-PCR (amplicon rescued multiplex PCR) and dam-PCR (dimmer avoided multiplex PCR) for highly efficient, quantitative, and automated multiplex PCR.As an entrepreneur, I founded Genaco in 1996 and grew it into a successful molecular diagnostic company. Qiagen acquired Genaco in 2006. I was also a co-founder of Diatherix, a CLIA-certified lab providing diagnostic services for infectious diseases. Eurofins acquired Diatherix in 2015. Both Genaco and Diatherix were using the tem-PCR technology. In 2009, I started two more companies, iCubate and iRepertoire, to commercialize arm-PCR and dam-PCR-based applications. ExperienceSpecialties: Developing Molecular diagnostic technologies, products, and integrating existing platforms to offer the customer a complete solution with unexpected user experience.

Experience

1. President, CSO

   Icubate Mdx

   Sep 2007 — Present

   Developing and marketing molecular differential diagnostic platform technology, iCubate. The iCubate platform allows sample extraction, amplification, and detection performed automatically, multiplexed and in a disposable and closed cassette.

Education

• Soochow University (CN)

  MD, Internal Medicine

  1978 — 1983

• University of Alabama at Birmingham

  Ph.D, Clinical Molecular Genetics

  1986 — 1991

Skills

• Dna
• Cell Culture
• Bioinformatics
• Lifesciences
• Purification
• Protein Expression
• Personalized Medicine
• Rna Isolation
• Technology Transfer
• Biomarkers
• Sequencing
• High Throughput Screening
• Biochemistry
• Commercialization
• In Vitro
• Dna Sequencing
• Microarray
• Drug Discovery
• Flow Cytometry
• Genetics
• Protein Chemistry
• Infectious Diseases
• Clinical Research
• Medical Diagnostics
• Western Blotting
• Pcr
• Tissue Culture
• Antibodies
• Molecular Biology
• Elisa
• Genomics
• Molecular Diagnostics
• Cell
• Vaccines
• Biomarker Discovery
• Microbiology
• Hardware Diagnostics
• Laboratory
• Drug Development
• Cancer