Jerry W. Skiles
Head of Chemistry at Microbiotix, Inc.
- Role
- Head of Chemistry at Microbiotix, Inc
- Location
- Worcester, MA, US
- LinkedIn followers
- 500 followers
About Jerry W. Skiles
Experience in all aspects of the pharmaceutical industry, from research and development, to clinical trials, preparation and submissions of INDs to the FDA, and cGMP regulatory issues. I also have prepared numerous presentations (both nationally and internationally), publications, patents, INDs, and grant proposals to the NIH. In addition I have served as the Project Team Leader in numerous therapeutic areas (i.e, diabetes and obesity, cardiovascular, anti-viral (HIV), inflammation, CNS, emphysema, and oncology). Specialties: Protease inhibitory design (metallo, aspartic, serine, cysteine), peptide and peptidomimetic chemistry, GPCRs, kinases inhibitor design, nuclear receptors, antifolates, nucleotides, siRNA, protein folding, heterocyclic chemistry, b-lactams, carotinoid chemistry, natural product isolation and synthesis, asymmetric synthesis, macrocyclic chemistry, asymmetric synthesis, kinetic resolution, photo-affinity labeling, process research and development, combinatorial chemistry, focused library generation, FBLD, and molecular modeling, protein homology building. Medicinal Chemistry, Process Research, CMC, cGMPs, Regulatory, INDs, patents (50), HTS analysis, SBIR grants, patent infringement expert.
Experience
Head of Chemistry
Mar 2023 — Present · Worcester, MA, US
Drug Discovery: Infectious diseases (viral and microbial), including multi-drug resistant pathogens.
Education
University of Pennsylvania
Ph.D., Organic Chemistry/ Total Synthesis Natural Products
Kent State University
BS, Chemistry
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