Jacopo Piazzi
Principal Clinical Trial Manager @Syneos Health
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WORK HISTORY
Principal Clinical Trial Manager @Syneos Health
Lead global Phase oncology programs involving 1,600+ patients across 400+ sites in 30+ countries.Accountable for end-to-end clinical trial delivery, including timelines, operational performance and cross-regional execution across EMEA, LATAM, APAC and North America.Operate in a high-complexity environment requiring continuous prioritization, risk management and alignment across multiple stakeholders, vendors and geographies.Key contributions:• Led global study teams and vendors across regions, ensuring alignment and performance in complex international trials• Drive study performance through oversight of operational metrics, enrollment and site performance across regions• Manage critical risks and escalations, coordinating cross-regional actions to maintain study timelines and delivery• Acted as primary operational interface with sponsors, contributing to governance discussions and decision making• Managed study budgets and resource allocation, tracking consumption and adjusting plans to keep studies aligned with both timelines and financial targets• Contribute to bid defense activities and strategic planning of global clinical programs.
EDUCATION
University of Siena (Università degli Studi di Siena)
Master of Engineering - MEng, Computer Engineering
University of Siena (Università degli Studi di Siena)
Ph.D., Engineering
SKILLS
ABOUT JACOPO PIAZZI
Clinical Operations leader with 19 years of experience leading global oncology trials across biotech and CRO environments. I operate in high-complexity settings, managing large-scale international studies across regions, vendors and stakeholders. My focus is on execution, performance and maintaining control in complex trials where timelines, quality and resources are constantly under pressure. My experience spans global Phase programs across EMEA, North America, LATAM and APAC, including large Phase oncology studies with >1,600 patients and 400+ sites. I bring a combination of hands-on operational leadership and program-level oversight, with direct experience in: • building and leading clinical operations teams • overseeing CRO and vendor networks • managing complexity across multi-country programs • driving risk-based decision making and operational performance Previously Director of Clinical Operations in a biotech company, where I built and led a team of ~20 professionals supporting a portfolio of ~15 concurrent trials across early and late-stage development. Currently working in a global CRO environment, leading large-scale international studies with direct exposure to sponsor governance and cross-regional decision making. My background in engineering and biostatistics supports a structured, data-driven approach, with a focus on performance, risk identification and financial oversight in complex clinical programs.
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