Jacob Salvatore

Research Associate Ii @Fulcrum Therapeutics

Cambridge, MA, US

Effectively culture primary CD34+ cells to complete disease biology experiments • Utilize CRISPR tools to create disease models to evaluate drug candidate efficacy• Implement automation tools for high- throughput screening and data collection• Screen compound efficacy in disease models using analytical techniques (RNA, gDNA extraction, and sequencing)• Collect vital data for regulatory filings and disease indication expansion • Implement Cryopreservation and Expansion protocol for cell banking, streamlining CD34+ selection process• Present high- impact experiment findings at department meetings to influence decision- making• Coordinate change control with material suppliers to insure seamless data collection • Organize lab tasks with team members to create optimal working conditions and compliance