Ivan Tesakov
Research Fellow (Translational Hematology and Immunology) @Universitätsklinikum Tübingen
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WORK HISTORY
Research Fellow (Translational Hematology and Immunology) @Universitätsklinikum Tübingen
Tübingen, DE
Engaged in translational research on the mechanisms of bone marrow failure and leukemia predisposition in chronic neutropenia within the group of Prof. Julia Skokowa and Prof. Karl Welte, combining clinical data analysis with in vitro disease modelling. Focused on uncovering cellular and molecular pathways driving chronic neutropenia to inform better diagnostics and therapeutic strategies.Key Responsibilities & Skills- Analyzing longitudinal data from the Severe Chronic Neutropenia International Registry (SCNIR) to assess disease course, prognosis, and risk of leukemic transformation- Conducting iPSC-derived hematopoietic differentiation and functional assays to model disease mechanisms in vitro- Integrating molecular, genetic, and phenotypic datasets to investigate neutrophil development and dysfunction- Collaborating across clinical hematology, stem cell biology, and molecular genetics to translate bench discoveries into patient-relevant insights- Experienced in iPSC-based modeling, flow cytometry, and data-driven translational researchThe results of the work have been published in Haematologica, Molecular Therapy, Experimental Hematology, and other journals.
EDUCATION
University of Tübingen
Doctoral degree in Medicine (Dr. med.)
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
Hematologist, Pediatric Hematology Residency Program
Moscow State University
Medical doctor (MD), Medicine
University of Tübingen
Doctoral degree in Experimental medicine (PhD)
ABOUT IVAN TESAKOV
Physician-scientist specializing in translational medicine, with clinical training in hematology and over six years of research experience in hemostasis, immunology, and cell biology. My research primarily focuses on bone marrow failure syndromes - especially hereditary platelet disorders and congenital neutropenia - and how intracellular signaling defects affect cell function in these diseases.
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