Hunter Smith
Undergraduate Research Assistant at Vanderbilt University Medical Center
- Role
- Undergraduate Research Assistant at Vanderbilt University Medical Center
- Location
- Chicago, IL, US
- LinkedIn followers
- 500 followers
About Hunter Smith
I am a recent Honors graduate from Vanderbilt University. I am now working at…
Experience
Undergraduate Research Assistant
Vanderbilt University Medical Center
Aug 2024 — Present · Nashville, TN, US
I will be investigating the role of Prostaglandin E2 (PGE2) as a potential mediator of trained immunity, a process whereby macrophages retain inflammatory memory after exposure to stimuli. Our preliminary, the Doran Lab\'s, data suggests macrophages primed with PGE2 exhibit an enhanced inflammatory cytokine response when re-stimulated but paradoxically display increased efficiency in efferocytosis, a key resolution process. Future work will explore the epigenetic and metabolic mechanisms underlying PGE2-induced trained immunity.
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