John Hsieh

About John Hsieh

Currently seeking opportunities in greater Boston or Taipei, Taiwan. I am a self-motivated and innovative biochemist. I have expertise in small-molecular kinase inhibitor drug development; for example, in small-molecule inhibitor screening, mechanistic enzymology, enzyme kinetics, and biophysical techniques. I have extensive experience in managing external CRO’s, contract management, LIMS, and working in a multi-disciplinary matrix in biotech and pharma. I am authorized to work in USA and Taiwan. Let\'s connect.

Experience

1. Principal Scientist, Biochemistry and Biophysics

   Blueprint Medicines

   Aug 2024 — Present · Cambridge, MA, US

   At Blueprint Medicines, I played a pivotal role in advancing clinical drug candidates through preclinical studies to IND filing. My responsibilities included designing enzymatic assays, performing compound library screenings, and managing biochemistry projects with external CROs. I also mentored interns, contributing to a collaborative and innovative environment. My work supported two key programs, BLU945 and BLU701, showcasing my commitment to impactful scientific research.

Education

• Texas A&M University

  B.Sc. with Honors, Biochemistry

  1986 — 1990

• Washington University School of Medicine in St. Louis

  Ph. D, Biochemistry

  1993 — 2002

Skills

• Pcr
• Enzyme Assays
• Fluorescence Spectroscopy
• Research
• Purification
• Protein Expression
• In Vitro
• Laboratory
• Fluorescence
• Biochemistry
• Molecular Biology
• High-Performance Liquid Chromatography (Hplc)
• Protein Chemistry
• Chromatography
• Cell Biology
• Science
• Assay Development
• Biophysics
• Antibodies
• Drug Discovery
• R&D
• Enzyme Kinetics
• High Throughput Screening
• Biotechnology
• Protein Purification
• Research and Development (R&D)
• Chemistry
• Life Sciences
• Cell Culture
• Cell Based Assays
• Pharmaceuticals
• Western Blotting
• Pharmaceutical Industry
• Dna
• Polymerase Chain Reaction (Pcr)