Heather Oakes
Principal Scientist @Lonza
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WORK HISTORY
Principal Scientist @Lonza
EDUCATION
University of Birmingham
Bachelor of Science (BSc), Biochemistry
SKILLS
ABOUT HEATHER OAKES
Biochemist with substantial experience in both the contract manufacturing bioanalysis sector and research in the pharmaceutical industry. Currently involved in the analysis of proteins by mass spectrometry for Product Characterisation, with a focus on monoclonal antibodies and experience of GMP.Introduction of new LC-MS systems to MS lab, and subsequent method development. Development of MS data processing workflows for newly implemented software. 2021/2022 On International assignment to implement MS technology for protein characterisation to a global site, including analyst training, method transfers and oversight of instrument instalation/qualification.Specialty: Mass Spectrometry (LC-MS) for protein characterisation eg intact mass, peptide mapping, disulphide bond analysis, glycan analysis, sequence variant analysis (including instrument and data processing method development).Instrumenation: Waters TOF/Q-TOF LC-MS (LCT, Q-TOF Micro, Xevo G2), Thermo Orbitrap Fusion with Dionex Bruker Impact IISoftware: Protein Metrics (PMi), MassLynx, BiopharmaLynx, Compass, Chromeleon, PEAKS Studio, Progenesis, PLGS
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