Gina M. Trabucco
Senior Scientist II at Novartis Institutes for BioMedical Research (NIBR)
- Role
- Senior Scientist Ii at Novartis
- Location
- Boston, MA, US
- LinkedIn followers
- 500 followers
Experience
Senior Scientist Ii
Jan 2014 — Present
Translational Immuno-Oncology -Support translational research activities for immunotherapies and combinations from early to late stage drug development-Manage CRO development, optimization, and validation of clinical flow cytometry biomarker panels-Analyze clinical trial patient biomarker data and create visualizations to inform team strategy-Multi-color flow cytometry panel development and optimization using BD Fortessa and Cytek Aurora instruments-FACS PD immunophenotyping of blood, immune cells, and tissue from healthy human donors, cancer patient biopsies, and various tumor-bearing mouse models-Preparation of human PBMCs from whole blood and MACS isolation and culturing of various immune cell types-Development of T-cell/cancer cell co-culture assay systems for testing compound potency and immune modulation functional readouts-Cytokine and other soluble factor analysis by MSD and ELISA-Immune cell memory evaluation by FACS and ELISPOT-Generation of monocyte-derived dendritic cells and testing compounds in DC/T-cell co-cultures-Tumor, lymph node, and spleen tissue dissociation in tumor-bearing mouse models for PD immunophenotyping-Tissue culture and cell line maintenance.
Education
Harvard University
Graduate Certificate
2017 — 2019
Harvard University
Master of Science - MS
2019 — 2023
University of Massachusetts, Amherst
Master of Science (M.S.)
2011 — 2012
University of Massachusetts, Amherst
Bachelor of Science (B.S.)
2006 — 2010
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