Ge Wei
Translational Medicine, discovery biology, PD/biomarker discovery, preclinical and clinical research, IND and NDA filings, targeted therapies, Oncology, immunotherapy and rare diseases
- Role
- Executive Director, Biology at Nurix Therapeutics
- Location
- San Francisco, CA, US
- LinkedIn followers
- 500 followers
About Ge Wei
A seasoned drug development leader in oncology, immunotherapy and rare diseases. Experienced in carrying drug candidates from discovery research, lead optimization to IND, clinical development to NDA. Proven record in leading translational research, biomarker discovery to support clinical trial strategy and CDx development, and FDA approval for 2 FDA approved drugs, ROZLYTREK (entrectinib, a ROS1/NTRK/ALK Inhibitor) and TRUSELTIQ (Infigratinib, an FGFR inhibitor). Experienced in leading in vitro and in vivo preclinical studies to evaluate the efficacy of drug candidates and MOAs, the combinations strategy, and MOAs of emerging resistance. Experienced in drafting documents to support IND and NDA filing. Capable to conceive, implement and guide R&D programs with excellent communications between laboratory staffs and senior management. Demonstrated success in multi-tasking and coordinating multiple projects, and consistently meeting aggressive time lines. A team player with leadership quality and cooperative spirit.Specialties: Drug discovery, translational research, Rx/Dx co-development, precision medicine, targeted and immune therapy, small molecules (inhibitors and bi-functional degraders) and biologics, PK/PD, biomarker, clinical development, oncology and rare genetic diseases, in vivo and vitro pharmacology, biochemistry and cell biology, glycobiology
Experience
Executive Director, Biology
Jul 2025 — Present
Education
Peking University
Master's degree, Biochemistry
1993
Peking University
Bachelor's degree, Biochemistry
1990
University of Alabama at Birmingham
Ph.D., Biochemistry and Molecular Genetics
1999
UC Santa Barbara Extension
Woman in Leadership Executive Program
2022 — 2023
Skills
- Drug Discovery
- Precision Medicine
- Dna
- Protein Purification
- Biomarker Development
- Cancer Research
- Cell
- Purification
- Protein Expression
- Molecular Cloning
- In Vitro
- Cell Biology
- Assay Development
- Drug Development
- Biochemistry
- Protein Chemistry
- In Vivo
- Clinical Development
- Translational Oncology
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