Gaelle Mercenne
Head of Biology | PhD, Pre-clinical Studies
- Role
- Head of Biology at Talus Bio
- Location
- Salt Lake City, UT, US
- LinkedIn followers
- 500 followers
About Gaelle Mercenne
Scientist and R&D leader with 10+ years of experience in drug discovery, AI-driven innovation, and translational research, with deep expertise in oncology, rare diseases, virology, and RNA biology.• Advanced programs to clinical candidate nomination, IND submission, and clinical trials• Applied AI/ML and computational tools to enable novel target discovery, patient stratification, and mechanism-of-action studies.• Led cross-functional, international teams and built global CRO partnerships to drive AI-enabled drug discovery and strategic execution.• Secured external funding by developing data packages and presenting at major conferences, including BIOEurope and BIO International.• Committed to translating complex biology into real-world therapies, with a focus on pediatric and underserved diseases.
Experience
Head of Biology
Sep 2024 — Present
Lead discovery and translational programs in oncology, neurology, and inflammatorydiseases, focusing on transcription factor targets; advanced multiple compounds from hitidentification to clinical candidate nomination. Collaborate closely with Proteomics and Data Science teams to drive target and compounddiscovery using Talus proprietary MARMOT platform, which integrates functional proteomicsand machine learning to study transcription factors in their native cellular context. Wrote several NIH and patient foundation grants and secured funding for several programs.
Education
University of Strasbourg
Doctor of Philosophy (PhD), Cell and Molecular Biology
2005 — 2009
Université de Rouen
Bachelor's Degree, Biochemistry and Molecular Biology
2000 — 2003
University of Strasbourg
Master of Science - MS, Cell and Molecular Biology
2003 — 2005
Skills
- Pcr
- Flow Cytometry
- Sds-Page
- Rna Isolation
- Transfection
- Drug Discovery
- Radioactivity
- Organization Skills
- Molecular Cloning
- Biochemistry
- Footprints
- Data Analysis
- Western Blotting
- Bl-3
- Cell Biology
- Protein Purification
- Dna Electrophoresis
- Crispr
- Assay Development
- Cell Culture
- Sop Development
- Lims
- Molecular Biology
- Rnai
- Project Management
- Virology
- Rna
- Hiv
- Protein Expression
- Immunoprecipitation
- Immunofluorescence
- Electron Microscopy
- Probing
- Glp
- Rt-Pcr
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