Frederick Goulette
Sr. Director of Scientific Affairs and Strategic Sourcing
- Role
- Director of Research and Development at Lang Pharma Nutrition
- Location
- Coventry, RI, US
- LinkedIn followers
- 500 followers
About Frederick Goulette
Publications: prior to 1994 omitted. Abstracts omitted. Darnowski JW, Goulette FA, Guan YJ, Chattered D, Yang ZF, Cousins LP, Chin YE. Stat3 cleavage by caspases: impact on full-length Stat3 expression, fragment formation, and transcriptional activity. J Biol. Chem. 2006 Jun 30; 281(26):17•••17. Cousins LP, Goulette FA, Darnowski JW. JAK-mediated signaling inhibits Fas ligand-induced apoptosis independent of de novo protein synthesis. J Immunol. 2005 Jan 1; 174(1):320-7. Darnowski JW, Goulette FA, Cousens LP, Chatterjee D, Calabresi P. Mechanistic and antineoplastic evaluation of taurolidine in the DU145 model of human prostate cancer. Cancer Chemotherapy Pharmacology 2004 Sep 54(3):249-58. Allegrini G, Goulette FA, Darnowski JW, Calabresi P. Thrombospondin-1 plus irinotecan: a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor engrafts in mice. Cancer Chemotherapy Pharmacology. 2004 Mar. Ribizzi I, Darnowski JW, Goulette FA, Akhtar MS, Chatterjee D, Calabresi P. Taurolidine: preclinical evaluation of a novel, highly selective, agent for bone marrow purging. Bone Marrow Transplant. 2002 Feb. Calabresi P, Goulette FA, Darnowski JW. Taurolidine: cytotoxic and mechanistic evaluation of a novel antineoplastic agent. Cancer Res. 2001 Sep 15; 61(18):6816-21. Ribizzi I, Darnowski JW, Goulette FA, Sertoli MR, Calabresi P. Amifostine cytotoxicity and induction of apoptosis in a human myelodysplastic cell line. Leuk Res. Jun;24(6):519-25. Davol PA, Goulette FA, Frackelton AR Jr, Darnowski JW. Modulation of p53 expression by human recombinant interferon-alpha2a correlates with abrogation of cisplatin resistance in a human melanoma cell line. Cancer Res. 1996 Jun 1;56(11):2522-6. Darnowski JW, Goulette FA. 3\'-Azido-3\'-deoxythymidine cytotoxicity and metabolism in the human colon tumor cell line HCT-8. Biochem. Pharmacol. 1994 Nov 1;48(9):17•••05.
Experience
Director of Research and Development
Jun 2011 — Present · Newport, RI, US
Lang Pharma Nutrition is a private label and corporate brand manufacturer specializing in supplements, beverages, bars, and foods with health and nutrition benefits. Member of interdisciplinary team charged with product research and formula development. This involves scientific literature review and laboratory analysis of novel ingredients to oversight of manufacturing facilities to ensure Lang’s commitment to quality via continuous good manufacturing practices and quality assurance/quality control.
Skills
- Research and Development (R&D)
- Scientific Review
- Gmp
- Clinical Development
- Research
- Cell Culture
- R
- Life Sciences
- Molecular Biology
- Clinical Nutrition
- Product Development
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