Florence Lee

About Florence Lee

Passionate, hands-on Assay Development Team Leader committed to impacting and improving cancer management for patients via developing accurate and timely diagnostic tests. Dedicated, collaborative, and committed to excellence, oversaw partnerships with 10+ major BioPharma companies and developed over 20 cell-based immunofluorescent, DNA-FISH and RNA-FISH assays to profile protein and nucleic acid biomarkers in circulating tumor cells (CTCs). • Scientific Expertise: oncology biomarker assay development, circulating tumor cells (CTCs), liquid biopsy, nuclear receptor-mediated transcriptional regulation, posttranslational modifications of nuclear receptors, hedgehog signaling, endocrine system development, lipoprotein, lipid and cholesterol metabolism, CNS-mediated appetite control and energy metabolismSpecialties: • Technical Expertise: genome-wide epigenetic analysis using native chromatin immunoprecipitation coupled with next generation sequencing, gene expression profiling techniques including microarrays and quantitative PCR, cell-based luciferase reporter assay, immunofluorescent assays, DNA-FISH, RNA-FISH, immunohistochemistry and in situ hybridization in cells and animal tissues, brightfield and confocal microscopy, mouse genetics, disease models in mice

Experience

1. VP, Clinical Development & Chief Scientist

   Truvian

   Nov 2025 — Present · San Diego, CA, US

Education

• UCLA

  B.S., Major in Biochemistry with minor in Classics

  1995 — 1999

• UCLA

  PhD, Molecular/Cell Biology, lipid metabolism, atherosclerosis

  2000 — 2006

Skills

• Laboratory
• Cell Biology
• Chromatin Immunoprecipitation
• Confocal Microscopy
• Life Sciences
• Molecular Cloning
• Animal Models
• Dna Sequencing
• Next Generation Sequencing Library Construction
• Ms Office Suite
• Microarray Analysis
• Graphpad Prism
• Immunostaining
• Fluorescence Microscopy
• Imagej
• Assay Development
• Cell
• In Situ Hybridization
• Qpcr
• Cell Culture
• Cell Based Assays