Fangyi Zhu
Senior Principal Scientist at Cambrex
- Role
- Senior Principal Scientist Technical Lead at Cambrex
- Location
- Durham, NC, US
- LinkedIn followers
- 500 followers
About Fangyi Zhu
Analytical chemist skilled in ADME, DMPK and toxicology studies to support the development of new drugs or other pharmaceutical products.Specialties: ADMET studies for new chemical entities;Pre-clinical toxicology, pharmacokinetics and efficacy studies (in vivo);LC/MS, LC/MS/MS and other bioanalytical methods (UV/ELSD) as a tool on a daily basis;PAMPA, uSOL;Drug formulation;Stability in SGF, liver microsome, plasmas;pH-solubility profile and pKa, logP, logD measurements;Protein binding.
Experience
Senior Principal Scientist Technical Lead
Apr 2023 — Present · Durham, NC, US
DMPK support for discovery of NCE• Bioanalytical method development, qualification and testing• Analytical method development, validation and testing• Extractable and Leachable• PGI/GTI method development, validation and testing, especially nitrosamines in drug substance and drug products• Lead MS-related analytical activities
Education
Beijing Institute of Technology
BS, Polymer Materials and Engineering
1993 — 1997
Purdue University
Ph.D.
2000 — 2004
Beijing Institute of Technology
MS, Materials Science
1997 — 2000
Skills
- Liquid Chromatography-Mass Spectrometry (Lc-Ms)
- Chemistry
- Drug Discovery
- Protein Purification
- Chromatography
- Dmpk
- Formulation
- Cell
- Protein Chemistry
- Laboratory Skills
- Purification
- Pharmacokinetics
- Cell Culture
- Lc-Ms
- Life Sciences
- Mass Spectrometry
- Biochemistry
- Hplc
- Adme
- Sds-Page
- Toxicology
- Laboratory
- Bioanalysis
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