Elizabeth Pratico
Cell and Gene Therapy Developer | CMC Technical Leader | Process, Analytical & Product Development
- Role
- Director at Moderna
- Location
- Boston, MA, US
- LinkedIn followers
- 500 followers
About Elizabeth Pratico
Accomplished director with a strong background in the biotech and pharmaceutical industry working with multiple modalities (CRISPR, LVV, AAV, and mRNA) to treat diseases, specializing in CMC technical leadership and pioneering cell and gene therapies from IND to Commercial. Proven proficiency in advancing allogeneic T cell therapies to treat cancer and developing cutting-edge autologous HSC and T cell-based ex vivo therapies. Expert in Cell Selection, Product Lifecycle Management (QbD), and Cellular Drug Product Development. Possesses advanced skills in Immunofluorescence, Immunoprecipitation, Flow Cytometry, In vitro methodologies, and Gel Electrophoresis. A collaborative and organized leader leveraging technical expertise and strategic vision to drive business development and foster innovation under rigorous timelines.Keywords: Cell Therapy, Gene Therapy, CMC Technical Leader, Process Development, Analytical Development, Product Development, Autologous HSC, T Cell Therapies, LVV, AVV, CRISPR Allogeneic Therapies, Cell Selection, Product Lifecycle Management, Immunofluorescence, Immunoprecipitation, Flow Cytometry, In Vitro, Gel Electrophoresis.
Experience
Director
Mar 2024 — Present · Norwood, MA, US
Leader of the Late Stage Engine focusing on Process Characterization DS Data Packages and enabling commercial filing readiness for Vaccines and Therapeutics.
Education
Ithaca College
B.A. Honors, Biochemistry
2000 — 2003
University of Illinois Urbana-Champaign
PhD, Biochemistry
Skills
- Flow Cytometry
- Immunofluorescence Imaging
- Selex
- Rna/Dna Extraction
- Cell Culture
- T Cell Isolation
- Proliferation Assays
- Sirna Knockdown
- Qt-Rt Pcr
- Protein Purification
- Biochemistry
- Dna
- Transfection
- Immunofluorescence
- In Vitro
- Rt-Pcr
- Cell
- Pcr
- Molecular Biology
- Protein Expression
- Western Blotting
- Cell Based Assays
- Assay Development
- Microbiology
- Translational Research
- Molecular Cloning
- Tissue Culture
- Experimental Design
- Qpcr
- Fluorescence Microscopy
- Protein Chemistry
- Laboratory
- Cell Biology
- Confocal Microscopy
- Elisa
- Rna Isolation
- Immunohistochemistry
- Fluorescence
- Gel Electrophoresis
- Enzyme Kinetics
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