Gopinath Krishnasamy

Computational Biology | Strain Development | Biotransformation | Biocatalysis | Drug Discovery l Enzyme Discovery and Engineering | Chemo-Enzymatic Peptide Synthesis (GLP-1)

Role
Associate Scientific Manager Ii - Api R & d at Biocon
Location
Bengaluru, KA, IN
LinkedIn followers
500 followers
Research & DevelopmentView LinkedIn profile

About Gopinath Krishnasamy

Dynamic Computational Biologist making significant contributions to the Biotransformation and strain development Team. Specializes in employing computational methodologies to identify and design biocatalysts, thereby enhancing the efficiency of enzymatic small molecule and peptide APIs (CEPS) synthesis. A dedicated researcher with a proven track record in Computer-Aided Drug Discovery, Enzyme Engineering, Natural Products, and Database Development. Recognized for fostering collaboration across interdisciplinary projects, driving seamless teamwork, and fostering innovation.

Experience

  1. Associate Scientific Manager Ii - Api R & d

    Biocon

    Jun 2022 — Present · Bengaluru, IN

    Key Responsibilities- Discovering and designing enzymes for the biocatalytic synthesis of small molecule and peptide APIs- Employing computational strategies to address scale-up challenges encountered in enzymatic small molecule and peptide API synthesis, ensuring efficient and effective execution of enzymatic processes- Supervising MultiOmics projects that integrate transcriptomic and genomic data to support strain engineering—encompassing differential expression analysis, whole-genome sequencing, pathway mapping, and functional annotation using protein language models- Supported in-house enzyme library and enzyme database projects- Contributed to establishing the computational laboratory within the Strain Development, Cell Culture, and Biotransformation Lab.

Education

  • Bharathiar University

    Master of Science (M.Sc.), Bioinformatics

    2007 — 2009

  • Periyar University

    Bachelor of Science (B.Sc.), Biotechnology

    2004 — 2007

  • Alagappa University, Alagappa Nagar, Karaikudi

    Doctor of Philosophy (Ph.D.), Bioinformatics

    2010 — 2015

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Gopinath Krishnasamy — Associate Scientific Manager Ii - Api R & d at Biocon in Bengaluru, KA, IN | Unifers