Nisha Peter
Senior Research Scientist @AstraZeneca
Signup · Get unlimited contacts
WORK HISTORY
Senior Research Scientist @AstraZeneca
Cambridge, GB
Lead and establish cellular workflows to triage peptides within the radio-conjugate portfolioDevelop and deliver robust, high quality, decision making cellular assay to support early drug discovery programs the AstraZeneca Oncology portfolio, within agreed timelinesScoping and evaluating new technologies to improve cellular drug discovery cascades for complex targets Experience with Cellular Thermal Shift (CETSA) assays designed for early chemical profiling, lead optimisation and high throughput screeningExperience in evaluating image analysis platforms e.g. Imagence (Genedata), Columbus and Cellomics as we all as training and supporting users on imaging assay buildsLed Safety Health and Environment (SHE) efforts within the team, streamlining process and ensuring compliance
EDUCATION
University of Sussex
Doctor of Philosophy (Ph.D.), Biochemistry
University of Mumbai
Master’s Degree, Biochemistry
University of Sussex
MSc, Genetic Manipulation and Molecular Cell Biology
Ramnarain Ruia College
Bachelor of Science (BSc), Biochemistry
ABOUT NISHA PETER
I am currently a Senior Research Scientist at AstraZeneca leading and establishing on-target and off-target cellular workflows for peptide radio-conjugates, small molecule and PROTAC, on Oncology projects. I have led the cell-biology work in the hit-to-lead phase of an Oncology project funded by Wellcome Trust, in collaboration with a leading pharmaceutical company. Within 1.5 years of my appointment, I have contributed to the nomination of a lead series by developing cellular target-engagement and phenotypic assays.I am well-versed in validating cellular targets to establish structure-function relationships and mechanistic studies. I have also contributed to three publications as a co-author.Skills: Preclinical research, Target validation, Target engagement (Drug Development), CRISPR/Cas9, Cell-line engineering, High-content imaging, Confocal and Wide-field Microscopy, Single Molecule Microscopy, Phenotypic assays, In-vitro assays, Internalisation assays
This profile is compiled from publicly available professional sources. Unifers is not affiliated with or endorsed by LinkedIn. Request removal of this profile.