Natalie Wu

About Natalie Wu

SUMMARY• Medical Affairs–oriented & PhD-trained Clinical Research Scientist with biopharma and CRO experience advancing clinical development programs in neuroscience, oncology, immunology, and pediatrics. Proven record supporting 8+ global clinical trials, delivering 15+ scientific presentations, and authoring 25 peer-reviewed publications.• Deep expertise applying next-generation seq and multi-omics approaches—including genomics, transcriptomics, epigenomics, and biomarker strategies—to elucidate disease mechanisms, identify therapeutic targets, and support precision medicine and clinical development.• Medical Affairs and Clinical Development experience includes KOL engagement, scientific exchange, clinical trial execution, and cross-functional collaboration with investigators, clinicians, and sponsors to support evidence generation and strategic development programs.• Strong scientific communications background with expertise in medical writing, peer-reviewed publications, congress presentations, and translating complex omics and clinical datasets into clear, actionable insights to support regulatory, clinical, and medical strategy.• Translational research leadership experience includes developing and validating genetically engineered and patient-derived disease models, biomarker discovery and validation, and integrating multi-omic datasets to support program strategy, target validation, and go/no-go decisions.• Collaborative and impact-driven scientist with experience spanning discovery research, translational biology, clinical trials, and medical affairs, bridging scientific innovation with clinical and patient impact.THERAPEUTIC AREAS OF EXPERTISE• Neuroscience/ Neuromuscular & Movement Disorders/ Multiple Sclerosis/ Huntington\'s Disease• Oncology / Neuro-Oncology / Solid Tumors• Immunology• Rare and neurodevelopmental disorders• Precision medicine and biomarker-driven therapeuticsSKILLS & PASSIONS• Medical Affairs & Field Medical collaboration• KOL Engagement & Scientific Exchange• Translational Research & Multi-Omics Integration• Biomarker Discovery & Precision Medicine• Clinical Development & Clinical Trials (Phases I–IV)• Scientific Communications & Medical Writing• Publications Strategy & Medical Congress Presentations• Target Identification & Mechanism-of-Action Studies• Cross-Functional Scientific Leadership• Translating complex omics and clinical data into strategic insightsHOBBIES: swing dancing, hiking/walking, ethnic cuisine, travel, pickleball, cooking* Let’s connect: w••••••••@gmail.com

Experience

1. Clinical Trial Manager

   Medpace

   Jan 2024 — Present

   Lead multinational Phase clinical trials across neuroscience, neuromuscular disease, immunology, rare disease, and gene/cell therapy, working closely with investigators, sponsors, and cross-functional teams to support trial design, execution, and clinical insight generation.• Build and maintain trusted relationships with 70+ KOLs and HCPs, supporting protocol feasibility discussions, enrollment strategies, safety data review, and bidirectional scientific exchange throughout trial execution.• Serve as the primary scientific and operational interface between clinical operations, sponsors, investigators, and vendors, aligning study goals, data quality, timelines, and clinical priorities while providing consistent, high-quality communication on study-specific questions.• Partner closely with investigators to translate complex study objectives, endpoints, and safety considerations into practical site-level execution, strengthening alignment between clinical practice and development strategy.• Contribute scientific and clinical input to protocol design, study plans, data review, and clinical study reports, supporting accurate interpretation of emerging safety and efficacy data.• Support ongoing review of clinical data and safety signals using Medidata Rave, achieving 100% query resolution and ensuring data quality suitable for downstream medical and regulatory use.• Lead and manage cross-functional study teams, including CRAs and vendors, to ensure compliance with ICH-GCP, regulatory standards, and sponsor expectations from start-up through closeout.• Manage operational risk assessment and execution for complex trial designs, including double-blind, dose-escalation, and open-label studies.• Support safety data collection and review as an unblinded CTM, working closely with investigators and safety teams to ensure timely identification and communication of relevant findings.

Education

• University of Zurich

  Master's degree, Neuroscience

• The University of Edinburgh

  Doctor of Philosophy - PhD, Neuroscience

  2008 — 2012