Ashish Sonkar
M. Pharm, PhD (Biological Science)
- Role
- Senior Research Investigator at Syngene International Limited
- Location
- Bengaluru, KA, IN
- LinkedIn followers
- 500 followers
About Ashish Sonkar
Pharmacokinetic/Toxicokinetic studies: In-vivo pharmacokinetics/toxicokinetics (bioavailability, excretion, tissue distribution, and dose proportionality studies) of xenobiotics in preclinical animals using the different routes of administration (Oral, I.V, S.C, etc.). Bio-analysis: Method development and validation for xenobiotics quantification in different matrices (e.g. blood, plasma, urine, tissues, and water, etc.) using UPLC, LC-MS/MS. In-vitro metabolism: Metabolic stability, CYP450/UGTs phenotyping & inhibition studies of xenobiotics using recombinant enzymes/microsomes/S9 fraction as a test system. Human pharmacokinetics prediction: In-vitro in-vivo extrapolation (IVIVE) using in-vitro and in-vivo preclinical data for predicting the pharmacokinetics/toxicokinetics in humans. Risk assessment: Integration of species difference in metabolism & toxicokinetics, and PBPK modeling for assessing the risk of environmental toxicants/toxins exposure on human health.
Experience
Senior Research Investigator
Aug 2025 — Present · Bengaluru, IN
Education
Rajiv Gandhi Prodyogiki Vishwavidyalaya
M.Pharm
2011 — 2013
UPTU, Lucknow
B.Pharma
2005 — 2009
Academy of Scientific and Innovative Research
Doctor of Philosophy - PhD
2015 — 2022
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