Diana Leite
Associate Principal Scientist @Sygnature Discovery
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WORK HISTORY
Associate Principal Scientist @Sygnature Discovery
Nottingham, GB
Project leader- Conception of novel research proposals and screening assay cascades to increase internal capabilities and income generation- Design and execution of robust assay development in projects spanning multiple therapeutics targets, with a strong emphasis on neuroscience and inflammation- Expanding expertise in in vitro neuroscience, including PSC-derived neurons and microglia, cell signalling pathways, lysosomal and mitochondrial assays, and neuronal outgrowth- Expertise in biophysical assays, cell biology assays, including cell viability, proliferation, migration, cell signalling, gene and protein assays- Communication and presentation of complex scientific ideas and datasets to key stakeholders- Scientific writing of peer-reviewed publications and white papers- Line managerial responsibilities.
EDUCATION
University of Portsmouth
Doctor of Philosophy - PhD
Faculdade de Engenharia da Universidade do Porto
Master's Degree
Universidade da Beira Interior
Bachelor's Degree
SKILLS
ABOUT DIANA LEITE
A highly motivated and accomplished multidisciplinary scientist with comprehensive research experience spanning both academic and drug discovery settings, complemented by proven project leadership and management capabilities, and a specialisation in neuroscience. My academic experience has cultivated a deep and specialised knowledge within neuroscience, focusing on the critical challenge of drug delivery across the blood-brain-barrier for developing treatments for neurodegenerative disorders and neuro-oncology. My tenure in drug discovery has equipped me with invaluable and highly-sought after expertise across the critical early-stage development pipeline, encompassing target identification and rigorous validation, the design and execution of robust assay development enabling efficient high-throughput screening campaigns, and the strategic guidance of lead optimisation efforts. Experience spans multiple therapeutic targets, which a strong emphasis in neuroscience and inflammation, providing me with an understanding of the underlying biology and drug discovery strategies relevant to a wide range of neurological, psychiatric and inflammatory conditions. I possess strong leadership skills in guiding and motivating scientific teams, coupled with proven managerial skills in effectively managing project timelines and resources, and ensuring successful execution of complex research goals. Adept to working independently and collaboratively within multidisciplinary teams, possessing excellent problem solving and critical thinking skills, and passionate about translating scientific breakthroughs into innovative solutions.
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