Dennis Obrien

About Dennis Obrien

I lead commercialization in obesity and cardiometabolic disease across traditional pharma and emerging digital health models. My experience spans market access, HCP and payer marketing, employer strategy, and go-to-market planning — all with a focus on making innovative therapies accessible, scalable, and financially sustainable.Over the past 10+ years, I’ve helped shape and launch major brands, including playing a leadership role in the commercialization and employer strategy for GLP-1 obesity treatments. The landscape is shifting quickly, and I’ve had a direct role in how employers, PBMs, payers, clinicians, and patients are reshaping expectations around affordability, evidence, and care delivery.I’m at my best when connecting strategy to execution. I simplify complex market dynamics into clear commercialization paths and build frameworks teams can operationalize. I focus on anticipating challenges early, ensuring payer, employer, and provider needs are aligned well before launch, and building repeatable models that scale.Ultimately, I’m motivated by improving how people living with chronic disease receive care, and doing it in a way that benefits patients, health systems, and the businesses responsible for delivering innovation.

Experience

1. Executive Director Obesity Commercial Strategy (Employer, Access & Go-to-market)

   Eli Lilly and Company

   Jun 2022 — Present · Indianapolis, IN, US

   Key Impact & Responsibilities:• Defined the U.S. employer commercial model for obesity, including segmentation, value proposition development, messaging hierarchy, and channel playbooks.• Designed and operationalized the employer engagement model—including governance, cross-functional collaboration processes, KPIs, analytics enablement, and reporting cadence.• Integrated employer insights into product and portfolio strategy across medical, HEOR, HCP marketing, access, policy, and consumer teams.• Developed engagement frameworks with PBMs, consultants, employer coalitions, and digital health partners to drive employer adoption and member activation.• Led enterprise mindset shift to position employers as long-term strategic partners in GLP-1 sustainability and chronic care management.Results: Enabled employer channel deployment that informed enterprise investment decisions and scaling roadmap.

Education

• Dowling College

  Bachelor's of Science, Business Administration and Management

  1997 — 2001

Skills

• Market Access
• Sales Operations
• Computer Proficiency
• Managed Markets
• Sales Effectiveness
• Biopharmaceuticals
• Hospital Sales
• Pharmaceutical Sales
• Pain Management
• Sales
• Selling Skills
• Nephrology
• Team Leadership
• Psychiatry
• Project Management
• Medical Devices
• Managed Care
• Business Operations
• Contract Negotiation
• Healthcare
• Neurology
• Market Analysis
• Endocrinology
• Sales Rep Training
• Strong Business Acumen
• Injectable
• Biologics
• Community Mental Health
• Diabetes
• Business Analytics
• Healthcare Reimbursement
• Cross-Functional Team Leadership
• Key Opinion Leaders
• Hospitals
• Rheumatology
• Product Launch
• Buy
• Biotechnology
• Specialty Pharmaceutical