Deepak Pokhrel

About Deepak Pokhrel

Experienced laboratory manager with a demonstrated history of working in the higher education as well as clinical industry. Skilled in Biomedical research with strong expertise in skills pertaining to basic as well as translational research including but not limited to cell culture, immuno blotting, animal studies,PCR, ELISA, immunohistochemistry among other laboratory skills, and scientific writing. Proficient in Microsoft Office. Graduated with masters degree in professional Biomedical Science and Biotechnology(BSBT) focused in Biomedical and Biotechnology studies from University of Colorado Anschutz Medical Campus as well as M.Sc (Medical Microbiology ) from Tribhuvan University, Nepal.

Experience

1. Scientist - in Vivo Pharmacology & Preclinical Sciences

   Recursion

   Mar 2022 — Present · Milpitas, CA, US

   In this role, I progressively expanded my technical expertise into broader scientific ownership-advancing from hands-on in vivo pharmacology as a Research Associate to independently designing, executing, and analyzing complex preclinical studies, while contributing to team development and fostering cross-functional collaboration.Designed and executed complex in vivo studies across oncology, fibrosis, and immunology, serving in Study Director (SD), Principal Investigator (PI), and Study Lead capacities. Utilized advanced dosing techniques (PO, IP, SC, IV, IT, IN), surgical procedures, tumor implantation, and necropsy. Streamlined workflows with LIMS systems (Climb, Study Log, Excel), improving operational efficiency and data integrity.Designed, executed, and managed non-GLP toxicology studies, including toxicokinetics analysis and comprehensive report drafting, to provide critical safety data supporting dose selection for IND-enabling preclinical programs.Developed and validated high-fidelity rodent models and established in-house clinical pathology reference ranges, accelerating preclinical timelines and enabling more informed decisions during lead optimization and IND-enabling phases.Championed Lean Six Sigma initiatives to optimize study designs, formulation workflows, and deviation management, achieving a reduction in process deviations and elevating team capabilities in formulation preparation.Partnered with data scientists, engineers, and external CROs to advance ML-driven InVivomics platforms, driving predictive toxicology insights and de-risking preclinical development pipelines.

Education

• Institute of Science and Technology (IOST), Tribhuvan University

  Bachelor of Science (BSc)

• Institute of Science and Technology (IOST), Tribhuvan University

  Proficiency Certificate Level (PCL), Biology

• Tribhuvan University

  Master of Science (MSc)

• University of Colorado Anschutz Medical Campus

  Master of Science (MS)