Danny Lee
Director @ Adcentrx Therapeutics | Medicinal Chemistry and Discovery Research in Antibody Drug Conjugates
- Role
- Director at Adcentrx Therapeutics
- Location
- San Diego, CA, US
- LinkedIn followers
- 500 followers
About Danny Lee
Passionate research scientist with >10 years of experience in drug discovery. Results-driven and innovative leader in the field of antibody-drug conjugates (ADCs), a proven modality for oncology with untapped opportunities in immunology. Strong track record of generating novel intellectual property, submission of IND applications, and management of external CRO collaborations. Leveraged deep expertise in synthetic chemistry, protein conjugation, and chemical biology to design and optimize key features of ADCs, including linker-payload chemistry, hydrophilic linkers, and biologically active molecules. Passionate about rigorous evaluation of clinical data and up-to-date gathering of competitive intelligence to stay ahead of the curve. My mission is to advance the science and technology of protein conjugates and deliver impactful solutions for patients in need.*All views and opinions expressed here are my own and do not represent those of my employer or any affiliated organization*
Experience
Director
Feb 2022 — Present · San Diego, CA, US
Responsibilities and achievements- Payload design and optimization of potency, permeability, ADME properties that are suited for drug-conjugates leading to IND submissions- Hydrophilic linkers that enable high DAR ADCs with mAb-like PK- Development of novel and efficient conjugation chemistries- Generation of novel IP leading to numerous patent applications- Management of multiple external CRO FTEs- Work closely with biology and protein science teams to develop unique assays and solve specific problems- Competitive intelligence: continuously monitor preclinical and clinical landscape to guide BD and clinical teams
Education
The University of Auckland
Doctor of Philosophy (Ph.D.), Chemistry
2007 — 2011
University of Chicago
Postdoctoral Scholar, Chemistry
2012 — 2015
University of Auckland
Doctor of Philosophy - PhD, Chemistry
The University of Auckland
Bachelor of Science (BSc), Organic Chemistry
2003 — 2005
The University of Auckland
BSc Honours, Medicinal Chemistry
2006 — 2006
Auckland Grammar Boys School
High School
1998 — 2002
Skills
- Protein Chemistry
- Chemistry
- Organic Chemistry
- Organic Synthesis
- Carbohydrate Chemistry
- Peptide Synthesis
- Protein Purification
- Analytical Chemistry
- Medicinal Chemistry
- Cell Culture
- Western Blotting
- Peptides
- Characterization
- Nmr
- Fluorescence
- Mass Spectrometry
- Purification
- Lc-Ms
- Chemical Biology
- Nuclear Magnetic Resonance (Nmr)
Find verified contacts for anyone on LinkedIn
Unifers gives sales teams verified emails and direct dials, enriched profiles, and outreach that lands in the inbox.
Free plan included · No credit card required
This profile is compiled from publicly available professional sources. Unifers is not affiliated with or endorsed by LinkedIn. Request removal of this profile.