Scott L Childs

About Scott L Childs

Scott L Childs email: s••••••@renovoresearch.comI am internationally recognized as a leading industrial researcher in my field, having authored three of the top six most cited primary research publications on pharmaceutical cocrystals and delivered over two dozen podium presentations. Entering the field academically in 1996 and then commercially in 2001, I became one of the pioneers in the renaissance of pharmaceutical cocrystals. I performed an essential role in the development and adoption of a technology that improves physical properties of drugs using a unique class of crystal form. As the only industrial researcher in the world focused specifically on cocrystals, I have maintained this focus as the concept transformed from blue-sky idea to adopted technology by engaging in a continuous research program that spanned positions at multiple large and small companies, including six years as a small-business owner and entrepreneur. The success of this technology can be measured in part by noting that in 2001 not one single commercial lab was screening for cocrystals, but today every large pharmaceutical company actively works with cocrystals.Specialties: Pre-clinical drug development, small molecule, solid form screening, characterization and formulation of pharmaceutical cocrystals, pre-formulation, formulation development, high-throughput screening.

Experience

1. CSO, Director of Research

   Renovo Research

   Sep 2008 — Present

   Renovo is a privately held boutique pharmacetutical company specializing in the commercialization of pharmaceutical cocrystals. Renovo identifies new, patentable, solid forms of active pharmaceutical ingredients (APIs) that can significantly improve the physical properties of the API. Improved properties of cocrystals are being exploited to improve the bioavailability of poorly soluble APIs by incorporating high solubility cocrystals into supersaturating drug delivery systems. • Responsibilities at Renovo include planning, staffing, laboratory management and coordinating all scientific, accounting, legal and business development activities • Received an SBIR Phase I Grant from the National Science Foundationin 2013 to study the integration of highly soluble cocrystals into supersaturating drug delivery systems • Experienced with equipment automation and systems integration. Designed and implemented the automation of X-ray powder diffraction and Raman spectroscopy instruments to collect high-throughput data. This included performing in-house fabrication and modification of equipment using CNC machining equipment. • Designed and manufactured a complete high-throughput solid form screening platform based take-apart reactor blocks with integrated stirring and sonication capabilities. Crystallization conditions include wet or dry milling, slurry conversion, evaporation, and precipitation. • Mentored direct reports to increase their capabilities and expertise; all direct reports were able to directly leverage high value skills gained at Renovo in their subsequent industry positions • Negotiated a strategic partnership agreement to obtain an equity stake in an API contingent on reaching milestones in the development of bioavailability and stability improving formulations

Education

• Emory University

  Doctor of Philosophy (PhD), Chemistry

  1993 — 2001

• Linfield University

  Bachelor of Arts (B.A.), Chemistry and Biology

  1988 — 1992

Skills

• Technology Transfer
• Cocrystals
• Tga
• Pharmacokinetics
• Sbir
• Formulation
• Commercialization
• Powder X-Ray Diffraction
• R&D
• High Throughput Screening
• Solubility
• X-Ray Crystallography
• Drug Development
• Pharmaceutical Industry
• Nmr
• Pharmaceutical Research
• Crystal Engineering
• Hplc
• Pxrd
• Raman
• Formulation of Cocrystals
• Polymorph Screening
• Chemistry
• Pharmaceutics
• Drug Discovery
• Organic Chemistry
• Cocrystal Screening & Characterization
• Crystallization
• Characterization
• Spectroscopy
• Analytical Chemistry
• Drug Delivery
• Dissolution
• Entrepreneurship
• Solid State Characterization