Clare Ridgway
Senior Scientist 2 @Sygnature Discovery
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WORK HISTORY
Senior Scientist 2 @Sygnature Discovery
Tytherington, GB
SKILLS
ABOUT CLARE RIDGWAY
Highly motivated Senior Scientist, with over 15 years laboratory and experimental design experience currently working within the fermentation industry and previously pharmaceutical drug safety and companion diagnostic industry. My strengths lie in the ability to research, develop, validate and execute bespoke and routine experimental work. I also have a wealth of experience in sourcing and co-coordinating outsourcing activities to address customer requirement to agreed timelines. Following the restructure at AstraZeneca my role was redundant, therefore I took a career break (Dec 2013 to Apr 2014) to work as a Chalet Host/Chef in the French Alps over the winter season. I returned to science working on a temporary contract for VWR for 2 months before taking a role in companion diagnostics at Qiagen and more recently the biologics industry working at Cobra Biologics within R&D using small scale fermentation to generate high quality plasmid DNA.KEY SKILLS:Laboratory skills include:o Fermentation: 250mL, 5L scale and 1L shaker flasks. o Molecular biology: Nucleotide extraction, quantification and analytics using AGE, AEX-HPLC, RT-PCR (TaqMan®)o Immunoassays: ELISA, Western bloto Endpoint assays: Cytotoxicity, Biochemical assay, High Content Biology Imagingo Cell culture: Primary cells and cell lines (adherent and suspension lines)o Subcellular isolationo Use of small scale automation and specialized laboratory equipment: PlateMate, Hamilton, DSX, MSD, QiaSymphony, SeahorseNon-laboratory skills:o Data analysis using Excel, Origin, Prismo Project management skills: Study plan, report, review and implemento Presentation skills: Powerpoint and confident verbal communication skillso Source, co-ordinate and monitor routine and bespoke outsourced experimental activitieso Maintain and work to GLP and GCP. o Standard Operating Procedure (SOP) co-ordinator
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