Christopher J. Nirschl

About Christopher J. Nirschl

With over ten years of experience in immunology and oncology research, I lead efforts at Werewolf Therapeutics as Director of Immunology. My work focuses on coordinating experimental strategies across in vivo and in vitro platforms while collaborating with teams in areas like protein engineering and biomarker development. I have contributed to integrating innovative technologies, such as the Lunaphore Comet and Cytek Aurora, into workflows to enhance research capabilities. My role encompasses scientific communication, including authoring multiple peer-reviewed manuscripts, and managing cross-functional teams to achieve research objectives. Leveraging my expertise in CRO management and a strong scientific background, I aim to drive impactful discoveries and advance cutting-edge therapeutic solutions in the field of immunology.

Experience

1. Director, Immunology

   Werewolf Therapeutics

   Jan 2025 — Present · Watertown, MA, US

   In this role, I served as the primary liaison between management and the lab based research team, coordinating experimental efforts across multiple team members. The experimental goals included both in vivo and in vitro efforts, as well as coordination with other teams across various areas of focus (i.e. protein engineering, CMC, PK/PD, clinical biomarkers, etc). I also served as one of the primary team members investigating new technologies such as the Lunaphore Comet system, and was responsible for overseeing their adoption and integration into our analysis workflow. I was also responsible for several aspects of scientific communication, acting as the first author to multiple peer reviewed manuscripts, as well as numerous posters which I presented at a variety of external conferences. I was also responsible for helping my team coordinate with external vendors, such as CROs, and managed external efforts such as CDX and PDX model development and subsequent testing of our treatment agents. I also played a backup role to the Immunology team, stepping in for hands on experimentation either in vivo or in vitro as needed to maintain team bandwidth and to help progress experimental efforts towards our goals in a timely manner.

Education

• The Johns Hopkins University School of Medicine

  Doctor of Philosophy (Ph.D.), Immunology

  2009 — 2014

• University of Virginia

  Bachelor of Arts (B.A.), Chemistry

  2005 — 2009

• University of Virginia

  Bachelor of Science (BS), Biology, General

  2005 — 2009

Skills

• Immunology
• Assay Development
• Immunohistochemistry
• Qpcr
• Clinical Research
• Translational Research
• Oncology
• Protein Expression
• Cell Culture
• Polymerase Chain Reaction (Pcr)
• Medical Research
• Vaccines
• Mouse Models
• In Vivo
• Antibodies
• Rt-Pcr
• Confocal Microscopy
• Facs
• Molecular Cloning
• Animal Models
• Science
• Western Blotting
• Life Sciences
• Cell
• Scientific Writing
• Data Analysis
• Research
• Microarray Analysis
• Tissue Culture
• Molecular Biology
• Rna Isolation
• Biotechnology
• Laboratory
• Cancer
• Experimental Design
• Pcr
• Transfection
• Biochemistry
• Cancer Research
• Elisa