Chen Runqiang

About Chen Runqiang

Self-motivated scientist with extensive experience in Cancer Biology, Molecular biology and Immunology Key strength in: Critical thinking • Problem solving • Quick learning • Research project planning, execution and management • Collaborative team member in dynamic research environment Expertise in: CAR-T • CAR -NK • In vivo and in vitro high-throughput screen • Flow cytometry (FACS) • Next-generation sequencing • bioinformatics analysis • Lentivirus • Retrovirus • Human and mouse tumor models • Primary immune cell isolation, culture and co-culture • Cytotoxicity • Cytokine analysis • Cell line development • luminescence • ELISA •Immunofluorescence • Cell based assays development and application • confocal microscopy • RT-PCR • Protein kinase and phosphatase • Enzymatic assays • Mass spectrometry

Experience

1. Senior Scientist, Car-t Immunotherapy

   Sorrento Therapeutics, Inc

   Sep 2016 — Present

   Designed and constructed CARs • Produced lentivirus of CARs • Developed T and NK cell in vitro functional assays including cytotoxicity, clone expansion and proliferation assays • Measured cytokine production using ELISA • Characterized anti-tumor efficacy of CAR-T cells using tumor mouse model • Developed the off-the-shelf CAR products against solid tumor

Education

• Kunming Institute of Zoology, Chinese Academy of Sciences

  Doctor of Philosophy (Ph.D.), Biochemistry and Molecular Biology

  2000 — 2005