Carole Chrvala
Epidemiologist & Global HEOR Strategist | Value Dossier Development, HTA Alignment & Scientific Narrative Architecture | Rare Disease & Oncology
- Role
- Senior Advisor at Ecne Research
- Location
- Raleigh-Durham-Chapel Hill, NC, US
- LinkedIn followers
- 500 followers
About Carole Chrvala
As founder of Health Matters, Inc, I am a senior epidemiologist and global evidence strategy consultant with more than 30 years of experience supporting complex therapeutic assets across the product lifecycle.I partner with pharmaceutical and biotechnology organizations across North America and international markets, helping teams align clinical evidence, value positioning, and scientific communications to withstand regulatory and payer scrutiny.My primary therapeutic focus includes rare and complex diseases in neurology, neuromuscular disorders, oncology, immunology, and cardiometabolic conditions.My work integrates Medical Affairs and Market Access priorities. I support organizations with:• Global Value Dossier (GVD) development and refresh• HTA-aligned value positioning• Objection handling frameworks• Comparative effectiveness framing• Scientific communications platform architecture• Publication and evidence strategy integration• Epidemiology and health economics & outcomes research (HEOR)I am most frequently engaged when evidence complexity, payer scrutiny, and cross-functional alignment demand disciplined narrative architecture rather than tactical content production.If your team is preparing for global launch, value narrative refinement, or cross-functional evidence alignment, I welcome a conversation.Specialties:• Rare Disease & Orphan Drug Strategy• Precision Oncology• Neurology & Neuromuscular Disorders• Comparative Effectiveness Framing• HTA Preparation• Global Value Narrative Integration
Experience
Senior Advisor
Dec 2025 — Present · US
Delivers strategic leadership and epidemiology expertise to support complex client engagements, uphold scientific integrity, and interpret real-world evidence to inform value demonstration, regulatory strategy, and stakeholder communications
Education
College of Wooster
BS, Psychology
University of Colorado Boulder
PhD, Epidemiology
Skills
- Outcomes Research
- Therapeutic Areas
- Infectious Diseases
- Pharmacovigilance
- Pharmaceutical Industry
- Dermatology
- Life Sciences
- Lifesciences
- Cardiovascular Disease
- Manuscript Development
- Strategic Consulting
- Clinical Trials
- Epidemiology
- Strategy
- Diabetes
- Medical Writing
- Poster Presentations
- Medical Affairs
- Biostatistics
- Publication Strategy
- Program Evaluation
- Scientific Writing
- Healthcare
- Neurology
- Instructional Design
- Publications
- Strategic Communications
- Cardiology
- Women's Health
- Publication Planning
- Research
- Hematology
- Biotechnology
- Health Economics and Outcomes Research
- Medical Devices
- Clinical Research
- Oncology
- Informatics
- Clinical Development
- Medicine
Find verified contacts for anyone on LinkedIn
Unifers gives sales teams verified emails and direct dials, enriched profiles, and outreach that lands in the inbox.
Free plan included · No credit card required
This profile is compiled from publicly available professional sources. Unifers is not affiliated with or endorsed by LinkedIn. Request removal of this profile.