Freeman
Associate Director, Center for Translational Pharmacology @St. Jude Children's Research Hospital - ALSAC
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WORK HISTORY
Associate Director, Center for Translational Pharmacology @St. Jude Children's Research Hospital - ALSAC
Memphis, TN, US
Responsible for leading and implementing preclinical pharmacokinetic (PK) studies, and for the administrative and scientific direction of the preclinical branch of SJCRH\'s Center for Translational Pharmacology. Managing provision of services to St. Jude faculty members, including bioanalytical methods development and validation, preclinical PK (and PD) study design, data acquisition and archiving, and pharmacometric analyses. Currently supervising three Ph.D. level analytical chemists.
EDUCATION
University of Pittsburgh
Pharm.D., Pharmacy
SKILLS
ABOUT FREEMAN
Strong background in preclinical and clinical PK/PD analyses of small molecules. Currently directing institutional preclinical operations branch of SJCRH\'s Center for Translational Pharmacology, which offers bioanalytical, study design, and data analysis services to client investigators. Previous pharmaceutical industry experience as Lead Clinical Pharmacologist for oncology programs, responsible for life cycle management vis-à-vis PK/PD/ClinPharm spanning discovery to early development. Career long involvement in M&S activities supporting translations into the clinic, with emphasis on preclinical PK/PD analyses and pharmacometrics. Currently supervising three Ph.D. level scientists responsible for LC MS/MS assay development and validation; previous positions also included supervisory experience. Experience in establishing and administrating a PK core lab, including oversight of equipment, budgeting, project prioritization, and scientific direction. Proficient with multiple software packages, including WinNonlin, Monolix, NONMEM, ADAPT, SAAM II, R, S-Plus, GraphPad, SigmaPlot, GastroPlus, and PKSim/MoBi.Specialties: Pharmacokinetics, pharmacodynamics, modeling and simulation, pharmacometrics, oncology drug discovery and development, preclinical models, ADMET, bioanalytical laboratory set-up and operations (non-GLP environment)
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