Bruno Perlatti
Head of Natural Products Chemistry at Hexagon Bio
- Role
- Principal Scientist at Hexagon Bio
- Location
- Menlo Park, CA, US
- LinkedIn followers
- 500 followers
About Bruno Perlatti
Innovative Natural Product Chemist with 10+ years of experience in metabolite discovery, isolation and structural elucidation. Proven leader of multidisciplinary teams and large-scale research programs in industry and academia. Successfully scaled processes to isolate high-value preclinical molecules, including ADC payloads. Committed to advancing small molecule discovery through natural products pipelines. Ph.D in Organic Chemistry from the Federal University of Sao Carlos (Brazil), with postdoctoral appointments at UTHealth Houston (Gerald Bills LAb) and UCLA (Yi Tang Lab). Currently Principal Scientist and Head of Natural Products Chemistry at Hexagon Bio, a biotech company focused on finding new drugs by turning nature\'s DNA into new medicines.Areas of Expertise: Natural Products Chemistry; Organic Chemistry; Biosynthesis; Analytical Chemistry; Microbiology; Synthetic Biology.Key Projects Highlights- Discovery of novel bioactive fungal natural products - Environmental strains isolation, high-throughput screening, scale-up, isolation, structural characterization, bioassays and mode of action determination- Development of AI- and ML- based methods for dereplication and prioritization of fungal strains based on genomic, metabolomic and bioactivity profiling- Genome mining and heterologous expression of fungal biosynthetic gene clusters (BGC)- Biotechnological prospection of novel microorganisms- Quali/Quantitative analytical method development, validation and application using LC-MS/MS, SEC-ELSD, NMR, GC-FID, GC-MS/MS, CE-UV, FTIR, TG, DSC.
Experience
Principal Scientist
Feb 2024 — Present · Menlo Park, CA, US
Education
UFSCar - Alumni
Doctor of Philosophy (Ph.D.), Organic Chemistry
2012 — 2016
UFSCar - Alumni
Master of Science (M.Sc.), Organic Chemistry
2010 — 2012
UFSCar - Alumni
B.Sc Chemistry, Chemistry
2004 — 2009
Skills
- Teaching
- Chromatography
- Biotechnology
- Estatística
- Rmn
- Chemistry
- English
- Nmr
- Hplc (Cromatografia Líquida De Alta Resolução)
- Validation
- Mass Spectrometry
- Gc-Fid
- Espectroscopia Uv/Visível
- Microbiology
- Cromatografia Gasosa
- Lifesciences
- Microsoft Office
- Microbiologia
- Gas Chromatography
- Ftir
- Validação
- Química Analítica
- Powerpoint
- Microsoft Excel
- Pesquisa
- Organic Chemistry
- R&D
- Docência
- Cromatografia
- Ciências Da Vida
- Analytical Chemistry
- Inglês
- Research
- Química Orgânica
- Espectrometria De Massa
- Microsoft Powerpoint
- Química
- Uv/Vis
- Gc-Ms
- Espectroscopia
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