Brittany Elliott
Senior Research Associate @Duke University Medical Center
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WORK HISTORY
Senior Research Associate @Duke University Medical Center
Durham, NC, US
Designing and executing experiments investigating the role of small nucleolar RNAs (snoRNAs) and the mechanism by which snoRNAs of the RPL13a locus impact oxidative stressHigh-throughput detection of RNA-RNA and RNA-Protein interactionsAssay development for detection of 2’-O-methylation and RNA modifications on mRNATechnical proficiencies in:Method development for detection of RNA-RNA interactions and RNA modifications, design and troubleshooting of next generation sequencing library preparation and analysis (eCLIP, CLASH), small RNA sequencing, protein and RNA immunoprecipitation, RT-qPCR, in vitro RNA transcription, modification and ligation, compartmental fractionation of RNA and protein, nucleoside UPLC -MS/MS preparation and analysis, gene silencing and overexpression, plasmid engineering, ROS measurement, nucleic acid and mRNA isolation, crosslinked RNA-protein isolation, metabolic assays (Seahorse), western blotting, ELISA, immunohistochemistry and microscopy, cell and tissue culture, cell based assays, cell reporter assays, metabolic labeling.
EDUCATION
University of South Carolina School of Medicine
Doctor of Philosophy (Ph.D.), Biomedical Science
Purdue University
Bachelor of Science (B.S.), Biology, General
SKILLS
ABOUT BRITTANY ELLIOTT
Self-motivated and enthusiastic RNA and nucleic acids scientist with a variety of research experiences. Most recent background focused on high-throughput detection of RNA modifications, RNA-RNA interactions and exploring the role that snoRNA-guided 2\'-O-methylation has on cell function and disease.
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