Brittany Youngs

Senior Scientist in DMPK at Stoke Therapeutics

Role
Senior Scientist at Stoke Therapeutics
Location
Cambridge, MA, US
LinkedIn followers
500 followers
Research & DevelopmentView LinkedIn profile

About Brittany Youngs

Experienced Scientist with a demonstrated history of working in the pharmaceuticals industry. Skilled in Communication, Public Speaking, Molecular Biology, Management, and Cell Culture. Strong research professional with a Master’s Degree focused in Basic Science - Molecular Biology and Biotechnology from Clarkson University.

Experience

  1. Senior Scientist

    Stoke Therapeutics

    Jan 2024 — Present · Bedford, MA, US

    Oversee the generation of immunogen and positive control for ADA at CROs.• Independently develop ADA testing methods and transfer to CROs to support qualification/validation of methods according to the regulatory guidance.• Manage CROs for implementing ADA assays for testing samples from non-clinical and clinical studies.• Review study protocols, manage critical reagent lots, and monitor GLP sample testing.• Develop analytical assays to quantitate oligonucleotides in biological matrices to understand absorption, metabolism, distribution, and excretion (ADME) of drug candidates.• As subject matter expert in analytical assays, help CROs in troubleshooting any potential issues.• Design and develop biomarker assays to support identification of PD and potential clinical safety biomarkers in collaboration with toxicologist. Help in pharmacokinetic (PK)/toxicokinetic analysis of preclinical studies.• Present results at cross-functional teams and lab meetings.• Maintain accurate documentation of experiments in Electronic Laboratory Notebook (ELN).• Prepare high quality reports from internal or external projects (as needed).• Help maintain the bioanalytical lab operations and facilitate the timely renewal of service contracts by working closely with lab scientists and facility managers.• May manages a direct report.• Author/review scientific reports.

Education

  • Clarkson University

    Bachelor, Science; Biology

    2010 — 2012

  • Clarkson University

    Master’s Degree, Basic Science - Molecular Biology and Biotechnology

    2014 — 2016

  • Jefferson Community College

    Associate's Degree, Business Administration

    2008 — 2009

Skills

  • Molecular Biology
  • Laboratory
  • Communication
  • Research
  • Pcr
  • Microsoft Office
  • Aseptic Technique
  • Microbiology
  • Teaching
  • Management
  • Photoshop
  • Public Speaking
  • Cell Culture
  • Microscopy

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Brittany Youngs — Senior Scientist at Stoke Therapeutics in Cambridge, MA, US | Unifers