Brian Root

R&D Director | Scaling Biotech & Diagnostics Teams | $40M+ Programs | FDA Regulated Products

Role
Healthcare Advisory Council at Cav Angels
Location
Charlottesville, VA, US
LinkedIn followers
500 followers
Healthcare & Human ServicesView LinkedIn profile

About Brian Root

I build and scale R&D teams that deliver.I’m a senior R&D leader with 15+ years of experience building biotech and diagnostics teams, leading 20–100+ researchers, and delivering products from concept through manufacturing and regulatory authorization. I specialize in turning complex science into executed product pipelines under aggressive timelines.I’ve led $40M+ development programs, including taking a molecular diagnostic from whiteboard to FDA Emergency Use Authorization in under 24 months, while coordinating science, engineering, manufacturing, quality, regulatory, and commercial teams. My leadership style is strategic and execution-driven—owning portfolio decisions, resource allocation, risk management, and team growth—without being hands-on at the bench.What I do best- Build and lead high-performing R&D teams (startup → scale-up)- Own R&D strategy, portfolio, and operating cadence - Deliver manufacturable, customer-focused products - Stand up new capabilities (diagnostics, biomanufacturing, AI-biology, protein design)- Align science, engineering, and business to hit timelinesImpact highlights- Led 20–100+ person cross-functional R&D organizations - Managed $40M+ flagship programs - Delivered FDA-authorized diagnostic products - Improved manufacturing readiness and yield - Led strategic external partnership engagement to accelerate growth

Experience

  1. Healthcare Advisory Council

    Cav Angels

    Nov 2024 — Present · Charlottesville, VA, US

    CAV Angels is a non-profit network composed of UVA alumni, faculty, parents, students, and friends of the University with the purpose of elevating the entrepreneurial ecosystem for UVA alumni by educating, connecting, funding, and mentoring the extended UVA startup community. The Healthcare Advisory Council focuses on due diligence of opportunities in the healthcare, biotech, and medtech space.

Education

  • Northwestern University

    PhD, Materials Science and Engineering

    2004 — 2009

  • Lafayette College

    B.S., Chemical Engineering

    2000 — 2004

Skills

  • Science
  • Biochemistry
  • Protein Chemistry
  • Commercialization
  • Biotechnology
  • Research and Development (R&D)
  • Life Sciences
  • Technology Transfer
  • Molecular Biology
  • Microfluidics
  • Assay Development
  • Microscopy
  • Nanotechnology
  • Lifesciences
  • Purification
  • Polymers
  • Dna
  • R&D
  • Chemistry

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Brian Root — Healthcare Advisory Council at Cav Angels in Charlottesville, VA, US | Unifers