Brian Francica
Cb-012 Technical Lead, Senior Scientist Ii @Caribou Biosciences
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WORK HISTORY
Cb-012 Technical Lead, Senior Scientist Ii @Caribou Biosciences
Berkeley, CA, US
Advanced company-wide goals by segmenting complex tasks into achievable milestones-Efficiently managed projects by ensuring timeline accountability -Influenced initiatives by communication and building consensus-Led cross-functional research team in preclinical and IND-enabling research; authored and enabled IND submission in conjunction with Regulatory and QA functions, resulting in FDA clearance -Led CB-012 translational science effort in tandem with CROs to set up translational schedule and biomarker strategy, validate clinical assays, and analyze and present clinical data for Ph1-Organized cross-functional team to perform Search and Evaluation for new targets and indications-Collaborated with VP of Translational Science and CSO to define next-generation programs and research directions-Authored research publications detailing MOA of CAR T cell activity in AML-Consulted for preclinical efforts in autoimmune indications, shaped targets and editing strategies to maximize PK/PD
EDUCATION
Johns Hopkins School of Medicine
Doctor of Philosophy (Ph.D.)
University of Virginia
Bachelor's of Science
ABOUT BRIAN FRANCICA
Immunologist with 9 years of biotech experience driving innovation in immunology and oncology, spanning small molecules, biologics, and engineered cell therapies. I’ve led discovery and translational programs from concept to IND, partnering with pharma and academia to accelerate drug development and secure critical funding. My work bridges deep scientific expertise with strategic execution—whether crafting strategy from early discovery to IND, shaping translational assays and clinical data collection, or presenting complex data to cross-functional stakeholders. I\'m passionate about seeing novel ideas with sound scientific and clinical basis get funded and come to fruition.
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