Brandon Stewart
Senior Scientist
- Role
- Senior Scientist at Novartis
- Location
- San Diego, CA, US
- LinkedIn followers
- 500 followers
About Brandon Stewart
Oligonucleotide chemist with extensive laboratory experience and results-driven approach…
Experience
Senior Scientist
Apr 2023 — Present · San Diego, CA, US
Contributed towards development of various 5’-phosphate modified siRNAs by automated solid phase oligonucleotides synthesis by utilizing MerMade12 synthesizer.•Co-led the efforts in developing an oligonucleotide workflow from synthesis to the final product to help support the ongoing siRNA delivery projects•Contributing the efforts on incorporation of conjugation sites at the middle position of siRNA sequence and conjugation of several NVS proprietary albumin binding motifs (either fatty acids or ligands)•Work within the cross-functional RNA Synthesis team, perform oligonucleotide synthesis on oligonucleotide synthesizers, deprotection, purification by HPLC, and annealing of oligonucleotides as well as characterization of the synthesized oligonucleotides using LC-MS and other analytical techniques.• Develop and optimize reaction conditions, characterize reaction impurities, troubleshoot in the synthesis and purification process, and determine the purity of synthesized compounds.• Analyze and interpret data independently; organize and present data in a clear manner.• Management of chemical, lab supply, and solvent inventories• Contribute to the team’s knowledge through updating scientific literature and discussions
Education
California State University, Fullerton
Bachelor's degree, Biochemistry
2012 — 2017
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