Brandon Mathern

Associate Director-Cell and Gene Therapy- Head of Manufacturing @ Lonza | MBA

Role
Associate Director- Cell and Gene Therapy- Head of Vv2d Manufacturing at Lonza
Location
Houston, TX, US
LinkedIn followers
500 followers

About Brandon Mathern

Highly motivated, goal-oriented operations leader with over 20 years of manufacturing experience across pharmaceutical and Cell and Gene Therapy environments, operating within cGMP/DEA-regulated facilities. Proven record of leading large, complex, aseptic manufacturing organizations through scale-up, operational excellence, and regulatory success. Track record includes scaling viral vector production by 300%+, achieving multiple zero-observation FDA and EMA inspections, and reducing deviation rates by 50%+ across multiple organizations. Recognized as a hands-on leader and mentor who develops high-performing teams, drives accountability, and consistently delivers strong production, quality, safety, and compliance outcomes. Demonstrated success in progressive management roles with increasing scope, responsibility, and impact.

Experience

  1. Associate Director- Cell and Gene Therapy- Head of Vv2d Manufacturing

    Lonza

    Oct 2021 — Present · Houston, TX, US

    In charge of manufacturing of VV2D at Lonza Houston site. Leading commercial team of approximately 150 people and 4 clean rooms.

Education

  • University of Colorado Denver

    MBA

    2007 — 2010

  • Black Hills State University

    B.S., Mathematics

    2000 — 2004

Skills

  • Six Sigma
  • Quality Assurance
  • Gmp
  • Cross-Functional Team Leadership
  • Pharmaceutical Industry
  • Sop
  • Fda
  • Quality System
  • V&V
  • Operations Management
  • Validation
  • Sap
  • Lean Manufacturing
  • Technology Transfer
  • Continuous Improvement
  • Manufacturing

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Brandon Mathern — Associate Director- Cell and Gene Therapy- Head of Vv2d Manufacturing at Lonza in Houston, TX, US | Unifers