Bingtao Tang
Senior Scientist at Vor
- Role
- Senior Scientist, Cancer Immunotherapy, Car-t at Vor Bio
- Location
- Cambridge, MA, US
- LinkedIn followers
- 500 followers
Experience
Senior Scientist, Cancer Immunotherapy, Car-t
Aug 2022 — Present · Cambridge, MA, US
Generate novel CAR-T constructs: binder screening, CAR-T hinge/transmembrane domain/co-stimulatory domain optimization, CAR-T cell enhancement (PD1-CD28 switch receptor, chimeric co-receptor CCR). •Lead and supervise junior scientists for CAR-T production (with lentiviral transduction and transposon), transduction efficiency improvement by optimization of lentiviral transfer vectors.•Characterize CAR T-cell phenotype and function with cell-based assays in vitro (CAR-T cell activation, cytotoxicity, cytokine release, proliferation, and persistence) and mouse models in vivo (IVIS, flow cytometry of cells from blood/spleen/bone marrow, tumor re-challenge).
Education
University of Illinois Urbana-Champaign
Master's degree, Physiology, General
2013 — 2015
Xi'an Jiaotong University
Bachelor’s Degree, Bioengineering
2009 — 2013
University of Illinois Urbana-Champaign
Doctor of Philosophy - PhD, Physiology, General (Cancer Immunotherapy)
2013 — 2020
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