Billy Tomaszewski
Discovery Scientist - Immuno-Oncology
- Role
- Scientist Iii, Research Oncology at Genentech
- Location
- San Francisco, CA, US
- LinkedIn followers
- 500 followers
About Billy Tomaszewski
https://wht10.github.io/cv/ Cancer Immunologist with 13 years of…
Experience
Scientist Iii, Research Oncology
Oct 2022 — Present · South San Francisco, CA, US
Nominated a new class of bispecific T-cell engager targets and generated preclinical data to support pipeline entry- Supervised a Scientist on completion of pipeline entry enabling experiments- Collaborated with protein engineering groups to generate preclinical bispecific T-cell engager tool molecules, and IHC reagents- Designed, executed, and analyzed scRNAseq experiments that generated hypotheses for mechanism of action underlying bispecific T-cell engager efficacy- Utilized the Xenium spatial transcriptomic assay to validate scRNAseq findings in-situ- Identified cell types in the tumor microenvironment of patients and preclinical models associated with bispecific T-cell engager response - Developed preclinical bispecific T-cell engager models that utilize fully murine molecules which target endogenously expressed tumor antigens in immunocompetent mice- Led a project that improved the efficacy of bispecific T-cell engagers in solid tumors via combination therapy
Education
Case Western Reserve University
BSE, Biomedical Engineering, with minors in Polymer Science and Engineering and Business Management
2012 — 2016
Duke University
Immunology PhD
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