Ben Phillippi

About Ben Phillippi

I specialize in de-risking autologous cell therapy manufacturing during tech transfer and clinical scale-up. My work sits at the intersection of science, engineering, and GMP manufacturing—ensuring that complex biological therapies are reliably and efficiently produced. With hands-on experience in tech transfer, process scale-up, and manufacturing support, I collaborate across multidisciplinary teams to troubleshoot, optimize, and validate production processes. I thrive in dynamic environments where scientific rigor and operational excellence are both essential, and I’m driven by the opportunity to bring transformative therapies to patients who need them most.

Experience

1. Senior Cell & Gene Therapy Msat Engineer

   赛默飞世尔科技

   Nov 2022 — Present · San Francisco, CA, US

   Led risk-based technology transfer of advanced therapy processes into GMP manufacturing, integrating quality risk management principles to ensure compliance and inspection readiness.Conducted comprehensive Facility Fit and GAP assessments to proactively identify GMP, comparability, and operational risks prior to manufacturing execution.Partnered closely with Quality to author and review critical GMP documentation, including SOPs, batch records, risk assessments, and technology transfer protocols, ensuring alignment with regulatory standards.Owned change controls, deviations, CAPAs, and effectiveness checks, driving timely resolution and strengthening Quality System integrity.Led cross-functional investigations and successfully closed multiple major product-impacting deviations, driving root cause resolution and strengthening process controls.Implemented structured Raw Material Risk Assessment frameworks to evaluate supplier and material risks impacting product quality and clinical consistency.Provided on-the-floor GMP oversight during manufacturing campaigns, assessing real-time deviations and mitigating quality and compliance risks.Contributed to Operational Excellence initiatives by tracking quality and compliance metrics to support continuous improvement and audit preparedness.Served as a technical liaison between Operations, Quality, and customers to ensure clarity of requirements and sustained compliance throughout technology transfer.

Education

• Ohio University

  Bachelor's degree, Chemical Engineering

  2010 — 2014

• Syracuse University

  Master's of Science (MS), Bioengineering

  2014 — 2017

Skills

• 3d Modeling
• Cdna Preparation
• Cell Culture
• Blender
• Microsoft Visio
• Chemcad
• Matlab
• Dynamic Mechanical Analysis
• Flow Cytometry
• Makerbot
• Rna Isolation
• Pcr
• Bio-Rad Iq5