Avanish Varshney
Boston Research Center Lead @WuXi Biologics
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WORK HISTORY
Boston Research Center Lead @WuXi Biologics
MA, US
Establishing Wuxi’s new Integrated Drug Discovery Center. Managing all operations, design and hiring key talents.• Working with CSO and leadership team to strategize integrated antibody discovery services platform.• Collaborating with several cross-functional groups from China site and advising bispecific and multi- specific antibody discovery programs development.
EDUCATION
All India Institute of Medical Sciences
Ph.D., Microbiology
Albert Einstein College of Medicine
Clinical Research Program 101: Fundamentals of Clinical Research
SKILLS
ABOUT AVANISH VARSHNEY
Self motivated Scientist with experience in performing cutting edge research in industrial and academic setting with focus on Antibody Drug Discovery and Development. Successfully completed several target validations studies for Oncology and Infectious Diseases. Strong interpersonal & communication skills, ability to handle multiple assignments under pressure, and consistently meet deadlines in fast paced environment. Lead projects in cross-functional teams settings and supervise junior scientists, associates, technicians, graduate students, clinical fellows, and undergraduate student projects to fulfill project goals. Managing projects in collaboration with external vendors and CROs, Well-developed skills in prioritizing, organization, decision-making, time management, troubleshooting projects.SkillsExpertise in all phases of antibody discovery (Immunology, Oncology and Infectious Diseases), Phage display, Hybridoma technology, immunization, antibody engineering & optimization, in vitro cell based functional assays (proliferation, activation, cytotoxicity, stimulation and neutralization assays), cell surface receptor binding assays, opsonophagocytic and internalization assay, Immunocytochemistry, cytokine profiling, MSD, High throughput Antibody screening (HTS), Flow Cytometry, FloJo, Graph Pad prism, antibody library preparation, panning, lead identification of antibodies, ELISA & Flow based Immunoassays, ScFv preparation, fab purification, PCR, ELISA, Cloning and expression of Antigen or Antibody in Prokaryotic or Eukaryotic vector Systems (HEK, CHO), Binding Kinetics, Octet, site directed mutagenesis, transformation, transfection, electroporation, PCR, restriction digestion, ligation, isotype switching, Handling of clinical samples, isolation of PBMCs, B cells, T cells, platelets or other cell types, animal handling, in vivo pharmacology (oncology and Infectious diseases), pharmacokinetics, toxicology under GLP and cGMP regulations, evaluation of scientific literature, database, Writing SOPs, animal protocols, technical reports for IND submission.
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