Ashok K. Sharma
Lead Computational Biologist | Multi-omics & AI/ML | Microbiome & Drug Safety | Data-Driven Therapeutics | Mentor & Educator
- Role
- Bioinformatics Scientist Ii - Digestive and Liver Diseases at Cedars-Sinai
- Location
- Davis, CA, US
- LinkedIn followers
- 500 followers
About Ashok K. Sharma
I am a Lead Computational Biologist with over 8 years of experience developing…
Experience
Bioinformatics Scientist Ii - Digestive and Liver Diseases
Sep 2024 — Present · Los Angeles, CA, US
Key role: Leading single-cell and multi-omics investigations in inflammatory bowel disease (IBD)- Analyzing single-nucleus RNA-seq data from matched patient samples (creeping fat, involved/uninvolved ileum, MAT), non-IBD controls, and gastric bypass tissue to explore cellular changes beyond immune cells in IBD pathology- Investigating host–microbe interactions in Crohn’s disease by analyzing deep RNA-seq of CD11b⁺ cells from inflamed and non-inflamed ileal and colonic regions to identify host transcriptional responses to pathobionts- Supporting multi-omics integration projects by developing and applying pre/post-integration strategies to uncover metabolome–microbiome interactions across cohorts- Providing computational support for microbiome data analysis, power analysis, and grant development across collaborative translational research projects.
Education
Indian Institute of Science Education and Research, Bhopal
Doctor of Philosophy - PhD
2012 — 2018
National Institute of Pharmaceutical Education and Research
Master of Science (M.S.)
2010 — 2012
Dr. Harisingh Gour University (Sagar University)
B.Pharm
2006 — 2010
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