Arun Paripati

Postdoctoral Researcher @Nationwide Children's Hospital

Columbus, OH, US

Led AAV mediated Gene therapy for ACTA1 based Nemaline Myopathy- Validation of therapeutic strategy in invitro (Patient primary cell lines)- Characterization of ACTA1-H40Y mice model- Engineering an AAV vector for therapy development- Vector Biodistribution, dose escalation and toxicity studies- iPSC preparation from patient fibroblast cells.Led AAV serotype screening for Schwann cell specific targeting- Intrathecal injection of different AAV serotypes- Different peripheral tissue extraction and bio distribution studies using microscopy.Played an active role in developing AAV-mediated gene therapy for CMT1B- Performed Intrathecal and systemic delivery of AAV vector into disease mice model- Conducted different mice behavior studies to assess the disease recovery-

University of Hyderabad

Ph.D

Pondicherry University

Masters in Biotechnology